Nifedipine EP Impurity B

Name: Nifedipine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-023251

About Nifedipine EP Impurity B

Nifedipine EP Impurity B is a pharmacopeial impurity of Nifedipine carrying the CAS registry number 50428-14-3. Formula C17H16N2O5, molecular weight 328.32 g/mol. Its systematic (IUPAC) name is dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)pyridine-3,5-dicarboxylate. Alternative names: Nifedipine - Impurity B and DehydronitrosoNifedipine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Nifedipine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Nifedipine EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Nifedipine

View every impurity, metabolite and intermediate we list for Nifedipine.

Nifedipine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Nifedipine EP Impurity B
Catalogue No.	VQ-023251
CAS Number	50428-14-3
IUPAC name	dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)pyridine-3,5-dicarboxylate
Molecular formula	C₁₇H₁₆N₂O₅
Molecular weight	328.32 g/mol
Exact mass	328.1059
Grade	Reference Standard
HSN code	38229090
InChIKey	MUZLTKGYFZENFW-UHFFFAOYSA-N
SMILES	CC1=C(C(=C(C(=N1)C)C(=O)OC)C2=CC=CC=C2N=O)C(=O)OC
PubChem CID	128034

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	0 / 7
TPSA	94.9 Å²
Synonyms	Nifedipine - Impurity B, DehydronitrosoNifedipine, 2,6-Ntp, nitrosonifedipine, 2,6-Dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester, Dehydronitroso Nifedipine, 4-(2-Nitrosophenyl)-2,6-dimethyl-3,5-dimethoxycarbonylpyridine, Dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)-3,5-pyridinedicarboxylate, 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(2-nitrosophenyl)pyridine, Dimethyl-2,6-Dimethyl-4-(2-Nitrosophenyl) Pyridine-3,5-Dicarboxylate, 3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(2-nitrosophenyl)-, dimethyl ester

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nifedipine EP Impurity B?

The CAS Registry Number of Nifedipine EP Impurity B is 50428-14-3. It is also known as Nifedipine - Impurity B, DehydronitrosoNifedipine, 2,6-Ntp.

What is the molecular formula and molecular weight of Nifedipine EP Impurity B?

Nifedipine EP Impurity B has the molecular formula C17H16N2O5 and a molecular weight of 328.32 g/mol. Its IUPAC name is dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)pyridine-3,5-dicarboxylate.

What is Nifedipine EP Impurity B used for?

Nifedipine EP Impurity B is supplied as a characterised reference material related to Nifedipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nifedipine EP Impurity B can I order?

We supply Nifedipine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nifedipine EP Impurity B?

Yes. Every lot of Nifedipine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nifedipine EP Impurity B be shipped internationally?

Yes. Nifedipine EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.