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Levothyroxine WS

Synonyms: O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine · (-)-Thyroxine · Levothyroxine · 3,3′,5,5′-Tetraiodo-L-thyronine

CAS No.51-48-9
FormulaC15H11I4NO4
Mol. weight776.87
Catalogue No.VQ-007542
PurityReference Standard
HSN38229090

Levothyroxine WS (CAS 51-48-9) – Levothyroxine reference standard. C15H11I4NO4, MW 776.87. COA included. Worldwide shipping from Vaqora Chemicals.

Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
250 mg
500 mg
1 g
Bulk / custom pack · kg to MT
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Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing

About Levothyroxine WS

Listed under CAS 51-48-9, Levothyroxine WS is a high-purity reference standard of Levothyroxine available from Vaqora Chemicals. Its molecular formula is C15H11I4NO4 and its molecular weight is 776.87 g/mol. Systematically, it is named (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid. Common synonyms include (-)-Thyroxine and Levothyroxine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Levothyroxine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Levothyroxine WS in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

  • Identification & assay
  • Method development & validation
  • QC reference material

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Specifications & identifiers

Chemical identifiers
Product nameLevothyroxine WS
Catalogue No.VQ-007542
CAS Number51-48-9
IUPAC name(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
Molecular formulaC15H11I4NO4
Molecular weight776.87 g/mol
Exact mass776.6867
GradeReference Standard
HSN code38229090
InChIKeyXUIIKFGFIJCVMT-LBPRGKRZSA-N
SMILESC1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)C[C@@H](C(=O)O)N
PubChem CID5819
Physical properties
Physical formSolid
LogP (XLogP3)2.4
H-bond donors / acceptors3 / 5
TPSA92.8 Ų
SynonymsO-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine, (-)-Thyroxine, Levothyroxine, 3,3′,5,5′-Tetraiodo-L-thyronine, 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine, 3,3',5,5'-Tetraiodo-L-thyronine, Henning, L-Thyroxin, Thyrax, Thyreoideum, Thyroxin, Thyroxina l

Safety & hazard information (GHS)

GHS07 Harmful / irritant
Harmful / irritant
GHS08 Health hazard
Health hazard

Signal word: Danger

Hazard statements

  • H302Harmful if swallowed
  • H361Suspected of damaging fertility or the unborn child
  • H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P317, P318, P319, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of Levothyroxine WS?

The CAS Registry Number of Levothyroxine WS is 51-48-9. It is also known as O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine, (-)-Thyroxine, Levothyroxine.

What is the molecular formula and molecular weight of Levothyroxine WS?

Levothyroxine WS has the molecular formula C15H11I4NO4 and a molecular weight of 776.87 g/mol. Its IUPAC name is (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid.

What is Levothyroxine WS used for?

Levothyroxine WS is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine WS can I order?

We supply Levothyroxine WS in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine WS?

Yes. Every lot of Levothyroxine WS is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine WS be shipped internationally?

Yes. Levothyroxine WS is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
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