Sertraline EP Impurity B (Freebase)

Name: Sertraline EP Impurity B (Freebase)
Brand: Vaqora Chemicals
SKU: VQ-006685

About Sertraline EP Impurity B (Freebase)

Sertraline EP Impurity B (Freebase) (CAS 52758-03-9) is a pharmacopeial impurity of Sertraline offered by Vaqora Chemicals. The compound has the formula C17H19N, corresponding to a molecular weight of 237.34 g/mol. Its systematic (IUPAC) name is (1R,4R)-N-methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine. Common synonyms include cis-Tametraline and Sertraline EP Impurity B.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Sertraline impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Sertraline EP Impurity B (Freebase) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Sertraline

View every impurity, metabolite and intermediate we list for Sertraline.

Sertraline impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Sertraline EP Impurity B (Freebase)
Catalogue No.	VQ-006685
CAS Number	52758-03-9
IUPAC name	(1R,4R)-N-methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine
Molecular formula	C₁₇H₁₉N
Molecular weight	237.34 g/mol
Exact mass	237.1517
Grade	Reference Standard
HSN code	38229090
InChIKey	NVXPZMLRGBVYQV-RHSMWYFYSA-N
SMILES	CN[C@@H]1CC[C@@H](C2=CC=CC=C12)C3=CC=CC=C3
PubChem CID	10609935

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	1 / 1
TPSA	12 Å²
Synonyms	(1R,4R)-1,2,3,4-Tetrahydro-N-methyl-4-phenyl-1-naphthalenamine, rel-(1R,4R)-1,2,3,4-Tetrahydro-N-methyl-4-phenyl-1-naphthalenamine, (1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine, cis-Tametraline, Sertraline EP Impurity B, 1-Naphthalenamine, 1,2,3,4-tetrahydro-N-methyl-4-phenyl-, cis-(+/-)-, 1-Naphthalenamine, 1,2,3,4-tetrahydro-N-methyl-4-phenyl-, (1R,4R)-rel-, Tametraline, cis-, Sertraline Impurity 34

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sertraline EP Impurity B (Freebase)?

The CAS Registry Number of Sertraline EP Impurity B (Freebase) is 52758-03-9. It is also known as (1R,4R)-1,2,3,4-Tetrahydro-N-methyl-4-phenyl-1-naphthalenamine, rel-(1R,4R)-1,2,3,4-Tetrahydro-N-methyl-4-phenyl-1-naphthalenamine, (1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine.

What is the molecular formula and molecular weight of Sertraline EP Impurity B (Freebase)?

Sertraline EP Impurity B (Freebase) has the molecular formula C17H19N and a molecular weight of 237.34 g/mol. Its IUPAC name is (1R,4R)-N-methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine.

What is Sertraline EP Impurity B (Freebase) used for?

Sertraline EP Impurity B (Freebase) is supplied as a characterised reference material related to Sertraline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sertraline EP Impurity B (Freebase) can I order?

We supply Sertraline EP Impurity B (Freebase) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sertraline EP Impurity B (Freebase)?

Yes. Every lot of Sertraline EP Impurity B (Freebase) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sertraline EP Impurity B (Freebase) be shipped internationally?

Yes. We export Sertraline EP Impurity B (Freebase) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.