NADPH

About NADPH

NADPH is a process intermediate or related compound of Nicotinamide carrying the CAS registry number 53-57-6. With the molecular formula C21H30N7O17P3, it has a molar mass of 745.4 g/mol. Alternative names: Dihydrocodehydrogenase II and Reduced triphosphopyridine nucleotide.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Process chemists and analysts use it when developing synthetic routes to Nicotinamide, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Nicotinamide

View every impurity, metabolite and intermediate we list for Nicotinamide.

Nicotinamide impurities

Specifications & identifiers

Chemical identifiers
Product name	NADPH
Catalogue No.	VQ-050114
CAS Number	53-57-6
IUPAC name	[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
Molecular formula	C₂₁H₃₀N₇O₁₇P₃
Molecular weight	745.4 g/mol
Exact mass	745.0911
HSN code	2933
InChIKey	ACFIXJIJDZMPPO-NNYOXOHSSA-N
SMILES	C1C=CN(C=C1C(=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)OP(=O)(O)O)O)O)O
PubChem CID	5884

Physical properties
Physical form	Solid
LogP (XLogP3)	-6.8
H-bond donors / acceptors	9 / 22
TPSA	364 Å²
Synonyms	Dihydronicotinamide-adenine dinucleotide phosphate, Dihydrocodehydrogenase II, Reduced triphosphopyridine nucleotide, Reduced Nicotinamide Adenine Dinucleotide Phosphate, beta-NADPH, dihydronicotinamide adenine dinucleotide phosphate, reduced nicotinamide-adenine dinucleotide phosphate, Nicotinamide-adenine dinucleotide phosphate, reduced, reduced Coenzyme II, dihydronicotinamide adenine dinucleotide-P, nadph hydride

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of NADPH?

The CAS Registry Number of NADPH is 53-57-6. It is also known as Dihydronicotinamide-adenine dinucleotide phosphate, Dihydrocodehydrogenase II, Reduced triphosphopyridine nucleotide.

What is the molecular formula and molecular weight of NADPH?

NADPH has the molecular formula C21H30N7O17P3 and a molecular weight of 745.4 g/mol.

What is NADPH used for?

NADPH is supplied as a characterised reference material related to Nicotinamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of NADPH can I order?

We supply NADPH, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with NADPH?

Yes. Every lot of NADPH is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can NADPH be shipped internationally?

Yes. We export NADPH worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.