Acemetacin

Name: Acemetacin
Brand: Vaqora Chemicals
SKU: VQ-021413

About Acemetacin

Vaqora Chemicals supplies Acemetacin, a high-purity reference standard of Acemetacin registered under CAS number 53164-05-9. The compound has the formula C21H18ClNO6, corresponding to a molecular weight of 415.8 g/mol. The IUPAC name is 2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyacetic acid. Alternative names: Acemetacine and TVX 3322.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Acemetacin, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Acemetacin is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Acemetacin

View every impurity, metabolite and intermediate we list for Acemetacin.

Acemetacin impurities

Specifications & identifiers

Chemical identifiers
Product name	Acemetacin
Catalogue No.	VQ-021413
CAS Number	53164-05-9
IUPAC name	2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyacetic acid
Molecular formula	C₂₁H₁₈ClNO₆
Molecular weight	415.8 g/mol
Exact mass	415.0823
Grade	Reference Standard
HSN code	38229090
InChIKey	FSQKKOOTNAMONP-UHFFFAOYSA-N
SMILES	CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)OCC(=O)O
PubChem CID	1981

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	1 / 6
TPSA	94.8 Å²
Synonyms	Acemetacine, TVX 3322, indomethacin carboxymethyl ester, indometacin glycolic ester, indomethacin glycolic ester, 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, carboxymethyl ester, indometacin carboxymethyl ester, 2-({2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl}oxy)acetic acid, 2-((2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetyl)oxy)acetic acid, 2-(2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetyloxy)acetic acid, 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid carboxymethyl ester, TVX 1322

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H310Fatal in contact with skin
H330Fatal if inhaled

Precautionary statements: P260, P262, P264, P270, P271, P280, P284, P301 + P316, P302 + P352, P304 + P340, P316, P320, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Acemetacin?

The CAS Registry Number of Acemetacin is 53164-05-9. It is also known as Acemetacine, TVX 3322, indomethacin carboxymethyl ester.

What is the molecular formula and molecular weight of Acemetacin?

Acemetacin has the molecular formula C21H18ClNO6 and a molecular weight of 415.8 g/mol. Its IUPAC name is 2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyacetic acid.

What is Acemetacin used for?

Acemetacin is supplied as a characterised reference material related to Acemetacin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Acemetacin can I order?

We supply Acemetacin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Acemetacin?

Yes. Every lot of Acemetacin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Acemetacin be shipped internationally?

Yes. Acemetacin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.