Tofacitinib Citrate

Name: Tofacitinib Citrate
Brand: Vaqora Chemicals
SKU: VQ-007806

About Tofacitinib Citrate

Listed under CAS 540737-29-9, Tofacitinib Citrate is a high-purity reference standard of Tofacitinib available from Vaqora Chemicals. With the molecular formula C22H28N6O8, it has a molar mass of 504.5 g/mol. Common synonyms include Tasocitinib citrate and Xeljanz.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Tofacitinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Tofacitinib Citrate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Tofacitinib

View every impurity, metabolite and intermediate we list for Tofacitinib.

Tofacitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Tofacitinib Citrate
Catalogue No.	VQ-007806
CAS Number	540737-29-9
Other CAS	477600-75-2
IUPAC name	2-hydroxypropane-1,2,3-tricarboxylic acid;3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile
Molecular formula	C₂₂H₂₈N₆O₈
Molecular weight	504.5 g/mol
Exact mass	504.1969
Grade	Reference Standard
HSN code	38229090
InChIKey	SYIKUFDOYJFGBQ-YLAFAASESA-N
SMILES	C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
PubChem CID	10174505

Physical properties
Physical form	Solid
H-bond donors / acceptors	5 / 12
TPSA	221 Å²
Synonyms	Tasocitinib citrate, Xeljanz, Xeljanz XR, CP-690550 citrate, Tasocitinib monocitrate, Tofacitinib monocitrate, Tofacitinib (CP-690550) Citrate, Tofacitinib (citrate), CP 690550 citrate (Tofacitinib citrate), 540737-29-9 (citrate), CP-690550 Citrate (Tofacitinib Citrate), Racemic Tasocitinib

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H360May damage fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tofacitinib Citrate?

The CAS Registry Number of Tofacitinib Citrate is 540737-29-9. It is also known as Tasocitinib citrate, Xeljanz, Xeljanz XR.

What is the molecular formula and molecular weight of Tofacitinib Citrate?

Tofacitinib Citrate has the molecular formula C22H28N6O8 and a molecular weight of 504.5 g/mol.

What is Tofacitinib Citrate used for?

Tofacitinib Citrate is supplied as a characterised reference material related to Tofacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tofacitinib Citrate can I order?

We supply Tofacitinib Citrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tofacitinib Citrate?

Yes. Every lot of Tofacitinib Citrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tofacitinib Citrate be shipped internationally?

Yes. Tofacitinib Citrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.