N-Methylphthalimide

Name: N-Methylphthalimide
Brand: Vaqora Chemicals
SKU: VQ-023134

About N-Methylphthalimide

Listed under CAS 550-44-7, N-Methylphthalimide is an impurity of Rivaroxaban available from Vaqora Chemicals. The compound has the formula C9H7NO2, corresponding to a molecular weight of 161.16 g/mol. Systematically, it is named 2-methylisoindole-1,3-dione. It is also known as Phthalimide, N-methyl- or 1H-Isoindole-1,3(2H)-dione, 2-methyl-.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Rivaroxaban to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer N-Methylphthalimide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rivaroxaban

View every impurity, metabolite and intermediate we list for Rivaroxaban.

Rivaroxaban impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Methylphthalimide
Catalogue No.	VQ-023134
CAS Number	550-44-7
IUPAC name	2-methylisoindole-1,3-dione
Molecular formula	C₉H₇NO₂
Molecular weight	161.16 g/mol
Exact mass	161.0477
Grade	Reference Standard
HSN code	38229090
InChIKey	ZXLYYQUMYFHCLQ-UHFFFAOYSA-N
SMILES	CN1C(=O)C2=CC=CC=C2C1=O
PubChem CID	11074

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	0 / 2
TPSA	37.4 Å²
Synonyms	Phthalimide, N-methyl-, 1H-Isoindole-1,3(2H)-dione, 2-methyl-, 2-methyl-isoindole-1,3-dione, 2-Methylisoindoline-1,3-dione, 2-Methyl-1H-isoindole-1,3(2H)-dione #, N-Nethylphthalimide, 1H-Isoindole-1, 2-methyl-, 2-methylbenzo[c]azoline-1,3-dione, 2-methylbenzo[c]azolidine-1,3-dione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Methylphthalimide?

The CAS Registry Number of N-Methylphthalimide is 550-44-7. It is also known as Phthalimide, N-methyl-, 1H-Isoindole-1,3(2H)-dione, 2-methyl-, 2-methyl-isoindole-1,3-dione.

What is the molecular formula and molecular weight of N-Methylphthalimide?

N-Methylphthalimide has the molecular formula C9H7NO2 and a molecular weight of 161.16 g/mol. Its IUPAC name is 2-methylisoindole-1,3-dione.

What is N-Methylphthalimide used for?

N-Methylphthalimide is supplied as a characterised reference material related to Rivaroxaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Methylphthalimide can I order?

We supply N-Methylphthalimide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Methylphthalimide?

Yes. Every lot of N-Methylphthalimide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Methylphthalimide be shipped internationally?

Yes. N-Methylphthalimide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.