Vancomycin EP Impurity B

About Vancomycin EP Impurity B

Vancomycin EP Impurity B is a pharmacopeial impurity of Vancomycin carrying the CAS registry number 555598-85-1. Its molecular formula is C66H74Cl2N8O25 and its molecular weight is 1450.2 g/mol. It is also known as Desamidovancomycin B.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Vancomycin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Vancomycin EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Vancomycin

View every impurity, metabolite and intermediate we list for Vancomycin.

Vancomycin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Vancomycin EP Impurity B
Catalogue No.	VQ-042817
CAS Number	555598-85-1
IUPAC name	(1S,2R,18R,19R,22S,26R,29R,41S)-49-[(2S,3R,4S,5S,6R)-3-[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5,15-dichloro-2,18,33,36,38-pentahydroxy-19-[[(2R)-4-methyl-2-(methylamino)pentanoyl]amino]-20,24,27,43,45-pentaoxo-7,13-dioxa-21,25,28,42,44-pentazaoctacyclo[27.14.2.23,6.214,17.18,12.130,34.010,26.035,40]henpentaconta-3,5,8(49),9,11,14,16,30(46),31,33,35(40),36,38,47,50-pentadecaene-22,41-dicarboxylic acid
Molecular formula	C₆₆H₇₄Cl₂N₈O₂₅
Molecular weight	1450.2 g/mol
Exact mass	1448.4142
Grade	Reference Standard
HSN code	38229090
InChIKey	OGMARHJAPWBNFA-LYRMYLQWSA-N
PubChem CID	169447648

Physical properties
Physical form	Solid
LogP (XLogP3)	-4.2
H-bond donors / acceptors	19 / 27
TPSA	525 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Vancomycin EP Impurity B?

The CAS Registry Number of Vancomycin EP Impurity B is 555598-85-1. It is also known as Desamidovancomycin B.

What is the molecular formula and molecular weight of Vancomycin EP Impurity B?

Vancomycin EP Impurity B has the molecular formula C66H74Cl2N8O25 and a molecular weight of 1450.2 g/mol.

What is Vancomycin EP Impurity B used for?

Vancomycin EP Impurity B is supplied as a characterised reference material related to Vancomycin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Vancomycin EP Impurity B can I order?

We supply Vancomycin EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Vancomycin EP Impurity B?

Yes. Every lot of Vancomycin EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Vancomycin EP Impurity B be shipped internationally?

Yes. We export Vancomycin EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.