Quetiepine EP Impurity B (Free Base)

Name: Quetiepine EP Impurity B (Free Base)
Brand: Vaqora Chemicals
SKU: VQ-006622

About Quetiepine EP Impurity B (Free Base)

Vaqora Chemicals supplies Quetiepine EP Impurity B (Free Base), a pharmacopeial impurity of Quetiapine registered under CAS number 5747-48-8. Its molecular formula is C17H17N3S and its molecular weight is 295.4 g/mol. The IUPAC name is 6-piperazin-1-ylbenzo[b][1,4]benzothiazepine. Alternative names: N-Desalkylquetiapine and 11-Piperazinodibenzo[b,f][1,4]thiazepine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Quetiapine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Quetiepine EP Impurity B (Free Base) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Quetiapine

View every impurity, metabolite and intermediate we list for Quetiapine.

Quetiapine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Quetiepine EP Impurity B (Free Base)
Catalogue No.	VQ-006622
CAS Number	5747-48-8
Other CAS	111974-74-4
IUPAC name	6-piperazin-1-ylbenzo[b][1,4]benzothiazepine
Molecular formula	C₁₇H₁₇N₃S
Molecular weight	295.4 g/mol
Exact mass	295.1143
Grade	Reference Standard
HSN code	38229090
InChIKey	JLOAJISUHPIQOX-UHFFFAOYSA-N
SMILES	C1CN(CCN1)C2=NC3=CC=CC=C3SC4=CC=CC=C42
PubChem CID	11369918

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 3
TPSA	52.9 Å²
Synonyms	N-Desalkylquetiapine, 11-Piperazinodibenzo[b,f][1,4]thiazepine, Norquetiapine, 7-chloro-2-(2-methylphenyl)-3,1-benzoxazin-4-one, N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine, 6-piperazin-1-ylbenzo(b)(1,5)benzothiazepine, 6-piperazin-1-ylbenzo[b][1,5]benzothiazepine, 11-(piperazin-1-yl)dibenzo[b,f][1,4]thiazepine, 11-(1-Piperazinyl)dibenzo[b,f][1,4]thiazepine, 11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine, Dibenzo[b,f][1,4]thiazepine, 11-(1-piperazinyl)-, N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P264, P270, P272, P280, P301 + P317, P302 + P352, P318, P319, P321, P330, P333 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Quetiepine EP Impurity B (Free Base)?

The CAS Registry Number of Quetiepine EP Impurity B (Free Base) is 5747-48-8. It is also known as N-Desalkylquetiapine, 11-Piperazinodibenzo[b,f][1,4]thiazepine, Norquetiapine.

What is the molecular formula and molecular weight of Quetiepine EP Impurity B (Free Base)?

Quetiepine EP Impurity B (Free Base) has the molecular formula C17H17N3S and a molecular weight of 295.4 g/mol. Its IUPAC name is 6-piperazin-1-ylbenzo[b][1,4]benzothiazepine.

What is Quetiepine EP Impurity B (Free Base) used for?

Quetiepine EP Impurity B (Free Base) is supplied as a characterised reference material related to Quetiapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Quetiepine EP Impurity B (Free Base) can I order?

We supply Quetiepine EP Impurity B (Free Base) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Quetiepine EP Impurity B (Free Base)?

Yes. Every lot of Quetiepine EP Impurity B (Free Base) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Quetiepine EP Impurity B (Free Base) be shipped internationally?

Yes. Quetiepine EP Impurity B (Free Base) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.