10-Hydroxy Naltrexone

About 10-Hydroxy Naltrexone

10-Hydroxy Naltrexone is a metabolite or degradation product of Naltrexone carrying the CAS registry number 604767-82-0. With the molecular formula C20H23NO5, it has a molar mass of 357.4 g/mol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Naltrexone, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 10-Hydroxy Naltrexone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Naltrexone

View every impurity, metabolite and intermediate we list for Naltrexone.

Naltrexone impurities

Specifications & identifiers

Chemical identifiers
Product name	10-Hydroxy Naltrexone
Catalogue No.	VQ-034872
CAS Number	604767-82-0
IUPAC name	(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9,13-trihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Molecular formula	C₂₀H₂₃NO₅
Molecular weight	357.4 g/mol
Exact mass	357.1576
Grade	Reference Standard
HSN code	38229090
InChIKey	SPLLFLBLAXVPPQ-KNQKJSHASA-N
SMILES	C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2C(C6=C4C(=C(C=C6)O)O5)O)O
PubChem CID	71749207

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	3 / 6
TPSA	90.2 Å²

Safety & hazard information (GHS)

Environmental hazard

Signal word: Warning

Hazard statements

H400Very toxic to aquatic life

Precautionary statements: P273, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 10-Hydroxy Naltrexone?

The CAS Registry Number of 10-Hydroxy Naltrexone is 604767-82-0. It is also known as (5alpha)-17-(Cyclopropylmethyl)-3,10,14-trihydroxy-4,5-epoxymorphinan-6-one, 17-(Cyclopropylmethyl)-3,10,14-trihydroxy-5alpha-4,5-epoxymorphinan-6-one.

What is the molecular formula and molecular weight of 10-Hydroxy Naltrexone?

10-Hydroxy Naltrexone has the molecular formula C20H23NO5 and a molecular weight of 357.4 g/mol. Its IUPAC name is (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9,13-trihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one.

What is 10-Hydroxy Naltrexone used for?

10-Hydroxy Naltrexone is supplied as a characterised reference material related to Naltrexone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 10-Hydroxy Naltrexone can I order?

We supply 10-Hydroxy Naltrexone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 10-Hydroxy Naltrexone?

Yes. Every lot of 10-Hydroxy Naltrexone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 10-Hydroxy Naltrexone be shipped internationally?

Yes. 10-Hydroxy Naltrexone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.