Loperamide EP Impurity H

About Loperamide EP Impurity H

Loperamide EP Impurity H is a pharmacopeial impurity of Loperamide carrying the CAS registry number 61299-42-1. Its molecular formula is C29H31ClN2O and its molecular weight is 459.0 g/mol. Its systematic (IUPAC) name is 4-[4-(4-chlorophenyl)-3,6-dihydro-2H-pyridin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide. Common synonyms include Dehydro Loperamide and Loperamide - Impurity H.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

This Loperamide impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Loperamide EP Impurity H is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Loperamide

View every impurity, metabolite and intermediate we list for Loperamide.

Loperamide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Loperamide EP Impurity H
Catalogue No.	VQ-022998
CAS Number	61299-42-1
IUPAC name	4-[4-(4-chlorophenyl)-3,6-dihydro-2H-pyridin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide
Molecular formula	C₂₉H₃₁ClN₂O
Molecular weight	459 g/mol
Exact mass	458.2125
Grade	Reference Standard
HSN code	38229090
InChIKey	UUHAGHSPKICYQY-UHFFFAOYSA-N
SMILES	CN(C)C(=O)C(CCN1CCC(=CC1)C2=CC=C(C=C2)Cl)(C3=CC=CC=C3)C4=CC=CC=C4
PubChem CID	15234083

Physical properties
Physical form	Solid
LogP (XLogP3)	5.7
H-bond donors / acceptors	0 / 2
TPSA	23.6 Å²
Synonyms	Dehydro Loperamide, Loperamide - Impurity H, 4-(4-(4-Chlorophenyl)-3,6-dihydropyridin-1(2H)-yl)-N,N-dimethyl-2,2-diphenylbutanamide, 4-[4-(4-Chlorophenyl)-3,6-dihydropyridin-1(2H)-yl]-N,N-dimethyl-2,2-diphenylbutanamide, Loperamide hydrochloride specified impurity H, 4-(4-(4-chlorophenyl)-5,6-dihydropyridin-1(2H)-yl)-N,N-dimethyl-2,2-diphenylbutanamide, 4-(4-Chlorophenyl)-3,6-dihydro-N,N-dimethyl-a,a-diphenyl-1(2H)-pyridinebutanamide, 4-[4-(4-chlorophenyl)-3,6-dihydro-2H-pyridin-1-yl]-N,N-dimethyl-2,2-diphenyl-butanamide

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Loperamide EP Impurity H?

The CAS Registry Number of Loperamide EP Impurity H is 61299-42-1. It is also known as Dehydro Loperamide, Loperamide - Impurity H, 4-(4-(4-Chlorophenyl)-3,6-dihydropyridin-1(2H)-yl)-N,N-dimethyl-2,2-diphenylbutanamide.

What is the molecular formula and molecular weight of Loperamide EP Impurity H?

Loperamide EP Impurity H has the molecular formula C29H31ClN2O and a molecular weight of 459 g/mol. Its IUPAC name is 4-[4-(4-chlorophenyl)-3,6-dihydro-2H-pyridin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide.

What is Loperamide EP Impurity H used for?

Loperamide EP Impurity H is supplied as a characterised reference material related to Loperamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Loperamide EP Impurity H can I order?

We supply Loperamide EP Impurity H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Loperamide EP Impurity H?

Yes. Every lot of Loperamide EP Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Loperamide EP Impurity H be shipped internationally?

Yes. Loperamide EP Impurity H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.