2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione 62457-35-6

About 2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione

2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione is an impurity of Rivaroxaban carrying the CAS registry number 62457-35-6. With the molecular formula C11H11NO4, it has a molar mass of 221.21 g/mol. The IUPAC name is 2-(2,3-dihydroxypropyl)isoindole-1,3-dione. It is also known as 3-Phthalimidylpropane-1,2-diol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Rivaroxaban to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rivaroxaban

View every impurity, metabolite and intermediate we list for Rivaroxaban.

Rivaroxaban impurities

Specifications & identifiers

Chemical identifiers
Product name	2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione
Catalogue No.	VQ-033597
CAS Number	62457-35-6
IUPAC name	2-(2,3-dihydroxypropyl)isoindole-1,3-dione
Molecular formula	C₁₁H₁₁NO₄
Molecular weight	221.21 g/mol
Exact mass	221.0688
Grade	Reference Standard
HSN code	38229090
InChIKey	GUUVCKWUQHAMTB-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=O)N(C2=O)CC(CO)O
PubChem CID	13166848

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	2 / 4
TPSA	77.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione?

The CAS Registry Number of 2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione is 62457-35-6. It is also known as 2-(2,3-Dihydroxypropyl)-1H-isoindole-1,3(2H)-dione, 3-Phthalimidylpropane-1,2-diol, 1-(3,4,5,6-Tetrahydrophthalimido)-2,3-dihydroxypropane.

What is the molecular formula and molecular weight of 2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione?

2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione has the molecular formula C11H11NO4 and a molecular weight of 221.21 g/mol. Its IUPAC name is 2-(2,3-dihydroxypropyl)isoindole-1,3-dione.

What is 2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione used for?

2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione is supplied as a characterised reference material related to Rivaroxaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione can I order?

We supply 2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione?

Yes. Every lot of 2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione be shipped internationally?

Yes. We export 2-(2,3-Dihydroxypropyl)isoindoline-1,3-dione worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.