Nisoldipine

Name: Nisoldipine
Brand: Vaqora Chemicals
SKU: VQ-032182

About Nisoldipine

Nisoldipine is a stable isotope labelled analogue related to Nisoldipine carrying the CAS registry number 63675-72-9. Formula C20H24N2O6, molecular weight 388.4 g/mol. Systematically, it is named 3-O-methyl 5-O-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate. Alternative names: Nisoldipin and Bay k 5552.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Nisoldipine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Nisoldipine

View every impurity, metabolite and intermediate we list for Nisoldipine.

Nisoldipine impurities

Specifications & identifiers

Chemical identifiers
Product name	Nisoldipine
Catalogue No.	VQ-032182
CAS Number	63675-72-9
IUPAC name	3-O-methyl 5-O-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Molecular formula	C₂₀H₂₄N₂O₆
Molecular weight	388.4 g/mol
Exact mass	388.1634
Grade	Reference Standard
HSN code	38229090
InChIKey	VKQFCGNPDRICFG-UHFFFAOYSA-N
SMILES	CC1=C(C(C(=C(N1)C)C(=O)OCC(C)C)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
PubChem CID	4499

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	1 / 7
TPSA	110 Å²
Synonyms	Nisoldipin, Bay k 5552, Bay-k-5552, Geomatrix 16e, Nisoldipine (stn), Nisoldipine SR, Syscor mr 10, Syscor mr 20, Syscor mr 30, 3-Isobutyl 5-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, BAY-k 5552

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H361Suspected of damaging fertility or the unborn child
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P264, P270, P273, P280, P301 + P317, P302 + P352, P317, P318, P321, P330, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nisoldipine?

The CAS Registry Number of Nisoldipine is 63675-72-9. It is also known as Nisoldipin, Bay k 5552, Bay-k-5552.

What is the molecular formula and molecular weight of Nisoldipine?

Nisoldipine has the molecular formula C20H24N2O6 and a molecular weight of 388.4 g/mol. Its IUPAC name is 3-O-methyl 5-O-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.

What is Nisoldipine used for?

Nisoldipine is supplied as a characterised reference material related to Nisoldipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nisoldipine can I order?

We supply Nisoldipine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nisoldipine?

Yes. Every lot of Nisoldipine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nisoldipine be shipped internationally?

Yes. Nisoldipine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.