Hydrocortisone EP Impurity L

Name: Hydrocortisone EP Impurity L
Brand: Vaqora Chemicals
SKU: VQ-021235

About Hydrocortisone EP Impurity L

Vaqora Chemicals supplies Hydrocortisone EP Impurity L, a pharmacopeial impurity of Hydrocortisone registered under CAS number 641-77-0. Formula C21H30O4, molecular weight 346.5 g/mol. Alternative names: Hydrocortisone Acetate EP Impurity B and Hydrocortisone - Impurity L.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Hydrocortisone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Hydrocortisone EP Impurity L is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Hydrocortisone

View every impurity, metabolite and intermediate we list for Hydrocortisone.

Hydrocortisone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Hydrocortisone EP Impurity L
Catalogue No.	VQ-021235
CAS Number	641-77-0
IUPAC name	(8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Molecular formula	C₂₁H₃₀O₄
Molecular weight	346.5 g/mol
Exact mass	346.2144
Grade	Reference Standard
HSN code	38229090
InChIKey	LCZBQMKVFQNSJR-UJPCIWJBSA-N
SMILES	CC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)O
PubChem CID	92827

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	2 / 4
TPSA	74.6 Å²
Synonyms	Hydrocortisone Acetate EP Impurity B, Hydrocortisone - Impurity L, Hydrocortisone Acetate - Impurity B, 21-Deoxycortisol, 11beta,17alpha-Dihydroxypregn-4-ene-3,20-dione, 11beta,17alpha-Dihydroxyprogesterone, 11beta,17-dihydroxypregn-4-ene-3,20-dione, 4-Pregnene-11beta,17alpha-diol-3,20-dione, 21-Deoxy Cortisol, 11-beta,17-alpha-Dihydroxypregn-4-ene-3,20-dione, 21-Dehydrohydrocortisone

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P260, P273, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydrocortisone EP Impurity L?

The CAS Registry Number of Hydrocortisone EP Impurity L is 641-77-0. It is also known as Hydrocortisone Acetate EP Impurity B, Hydrocortisone - Impurity L, Hydrocortisone Acetate - Impurity B.

What is the molecular formula and molecular weight of Hydrocortisone EP Impurity L?

Hydrocortisone EP Impurity L has the molecular formula C21H30O4 and a molecular weight of 346.5 g/mol. Its IUPAC name is (8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one.

What is Hydrocortisone EP Impurity L used for?

Hydrocortisone EP Impurity L is supplied as a characterised reference material related to Hydrocortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydrocortisone EP Impurity L can I order?

We supply Hydrocortisone EP Impurity L in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydrocortisone EP Impurity L?

Yes. Every lot of Hydrocortisone EP Impurity L is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydrocortisone EP Impurity L be shipped internationally?

Yes. Hydrocortisone EP Impurity L is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.