Entecavir EP Impurity F

About Entecavir EP Impurity F

Entecavir EP Impurity F is a pharmacopeial impurity of Entecavir carrying the CAS registry number 649761-24-0. With the molecular formula C27H31N5O2Si, it has a molar mass of 485.7 g/mol. It is also known as Entecavir USP Impurity A or Entecavir USP Impurity F.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Entecavir impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Entecavir EP Impurity F in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Entecavir

View every impurity, metabolite and intermediate we list for Entecavir.

Entecavir impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Entecavir EP Impurity F
Catalogue No.	VQ-022540
CAS Number	649761-24-0
IUPAC name	2-amino-9-[(1S,3R,4S)-4-[dimethyl(phenyl)silyl]-2-methylidene-3-(phenylmethoxymethyl)cyclopentyl]-1H-purin-6-one
Molecular formula	C₂₇H₃₁N₅O₂Si
Molecular weight	485.7 g/mol
Exact mass	485.2247
Grade	Reference Standard
HSN code	38229090
InChIKey	LMLFXMXUWHGHSR-VABKMULXSA-N
SMILES	C[Si](C)([C@H]1C[C@@H](C(=C)[C@@H]1COCC2=CC=CC=C2)N3C=NC4=C3N=C(NC4=O)N)C5=CC=CC=C5
PubChem CID	136096441

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 4
TPSA	94.5 Å²
Synonyms	Entecavir USP Impurity A, Entecavir USP Impurity F, Entecavir Monohydrate - Impurity F, 6-O-Benzyl-4-dehydroxy-4-diMethylphenylsilyl Entecavir, 3-Benzyl-4-silyl entecavir, 9-((1S,3R,4S)-4-Dimethylphenylsilyl-3-(benzyloxymethyl)-2-methylenecyclopentyl)guanine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Entecavir EP Impurity F?

The CAS Registry Number of Entecavir EP Impurity F is 649761-24-0. It is also known as Entecavir USP Impurity A, Entecavir USP Impurity F, Entecavir Monohydrate - Impurity F.

What is the molecular formula and molecular weight of Entecavir EP Impurity F?

Entecavir EP Impurity F has the molecular formula C27H31N5O2Si and a molecular weight of 485.7 g/mol. Its IUPAC name is 2-amino-9-[(1S,3R,4S)-4-[dimethyl(phenyl)silyl]-2-methylidene-3-(phenylmethoxymethyl)cyclopentyl]-1H-purin-6-one.

What is Entecavir EP Impurity F used for?

Entecavir EP Impurity F is supplied as a characterised reference material related to Entecavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Entecavir EP Impurity F can I order?

We supply Entecavir EP Impurity F in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Entecavir EP Impurity F?

Yes. Every lot of Entecavir EP Impurity F is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Entecavir EP Impurity F be shipped internationally?

Yes. We export Entecavir EP Impurity F worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.