3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-… 66148-19-4

Name: 3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4
Brand: Vaqora Chemicals
SKU: VQ-038622

About 3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4

3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4 (CAS 66148-19-4) is a stable isotope labelled analogue related to Nicotine offered by Vaqora Chemicals. Formula C9H11N3O, molecular weight 181.23 g/mol. The IUPAC name is 2,3,4,6-tetradeuterio-5-(1-nitrosopyrrolidin-2-yl)pyridine. It is also known as rac N`-Nitrosonornicotine-d4 or N-Nitrosonornicotine-2,4,5,6-d4(Pyridine-d4).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Nicotine and related analytes in bioanalytical, pharmacokinetic and impurity studies. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Nicotine

View every impurity, metabolite and intermediate we list for Nicotine.

Nicotine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4
Catalogue No.	VQ-038622
CAS Number	66148-19-4
IUPAC name	2,3,4,6-tetradeuterio-5-(1-nitrosopyrrolidin-2-yl)pyridine
Molecular formula	C₉H₁₁N₃O
Molecular weight	181.23 g/mol
Exact mass	181.1153
Grade	Reference Standard
HSN code	38229090
InChIKey	XKABJYQDMJTNGQ-DNZPNURCSA-N
SMILES	[2H]C1=C(C(=C(N=C1[2H])[2H])C2CCCN2N=O)[2H]
PubChem CID	12147171

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	0 / 4
TPSA	45.6 Å²
Synonyms	rac N`-Nitrosonornicotine-d4, N-Nitrosonornicotine-2,4,5,6-d4(Pyridine-d4), (+-)-5-(1-Nitroso-2-pyrrolidinyl)pyridine-2,3,4,6-d4, rac N'-Nitrosonornicotine-D4, N'-Nitrosonornicotine-d4, N-Nitrosonornicotine-d4, ( inverted exclamation markA)-N inverted exclamation marka-Nitrosonornicotine-2,4,5,6-d4, (+/-)-N'-Nitrosonornicotine-d4 (pyridine-d4), NO-Nitrosonornicotine-D4, rac N-Nitrosonornicotine-d4

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H350May cause cancer

Precautionary statements: P203, P264, P270, P280, P301 + P316, P318, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4?

The CAS Registry Number of 3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4 is 66148-19-4. It is also known as rac N`-Nitrosonornicotine-d4, N-Nitrosonornicotine-2,4,5,6-d4(Pyridine-d4), (+-)-5-(1-Nitroso-2-pyrrolidinyl)pyridine-2,3,4,6-d4.

What is the molecular formula and molecular weight of 3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4?

3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4 has the molecular formula C9H11N3O and a molecular weight of 181.23 g/mol. Its IUPAC name is 2,3,4,6-tetradeuterio-5-(1-nitrosopyrrolidin-2-yl)pyridine.

What is 3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4 used for?

3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4 is supplied as a characterised reference material related to Nicotine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4 can I order?

We supply 3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4?

Yes. Every lot of 3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4 be shipped internationally?

Yes. 3-(1-Nitrosopyrrolidin-2-yl)pyridine-2,4,5,6-d4 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.