Capecitabine EP Impurity A

Name: Capecitabine EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-006282

About Capecitabine EP Impurity A

Capecitabine EP Impurity A (CAS 66335-38-4) is a pharmacopeial impurity of Capecitabine offered by Vaqora Chemicals. The compound has the formula C9H12FN3O4, corresponding to a molecular weight of 245.21 g/mol. The IUPAC name is 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoropyrimidin-2-one. Common synonyms include 5'-Deoxy-5-fluorocytidine and 5-Fluoro-5'-deoxycytidine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Capecitabine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Capecitabine EP Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Capecitabine

View every impurity, metabolite and intermediate we list for Capecitabine.

Capecitabine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Capecitabine EP Impurity A
Catalogue No.	VQ-006282
CAS Number	66335-38-4
Other CAS	1373281-84-5, 1373281-85-6, 1373281-86-7
IUPAC name	4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoropyrimidin-2-one
Molecular formula	C₉H₁₂FN₃O₄
Molecular weight	245.21 g/mol
Exact mass	245.0812
Grade	Reference Standard
HSN code	38229090
InChIKey	YSNABXSEHNLERR-ZIYNGMLESA-N
SMILES	C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=NC2=O)N)F)O)O
PubChem CID	10037499

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.6
H-bond donors / acceptors	3 / 5
TPSA	108 Å²
Synonyms	5'-Deoxy-5-fluorocytidine, 5-Fluoro-5'-deoxycytidine, 5'-DFCR, Cytidine, 5'-deoxy-5-fluoro-, Cytidine, 5'-deoxy-5-fluoro, 5'-Deoxy-5-fluoro Cytidine, 5`-Deoxy-5-fluorocytidine, Capecitabine impurity A CRS, 5\'-Deoxy-5-fluorocytidine, 5'-Deoxy-5-fluoro-D-cytidine, 5'-Deoxy-5-fluorocytidine (5'-DFCR), 1-(5-Deoxy-b-D-ribofuranosyl)-5-fluorocytidine

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H350May cause cancer
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P264, P264 + P265, P273, P280, P302 + P352, P305 + P351 + P338, P318, P321, P332 + P317, P337 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Capecitabine EP Impurity A?

The CAS Registry Number of Capecitabine EP Impurity A is 66335-38-4. It is also known as 5'-Deoxy-5-fluorocytidine, 5-Fluoro-5'-deoxycytidine, 5'-DFCR.

What is the molecular formula and molecular weight of Capecitabine EP Impurity A?

Capecitabine EP Impurity A has the molecular formula C9H12FN3O4 and a molecular weight of 245.21 g/mol. Its IUPAC name is 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoropyrimidin-2-one.

What is Capecitabine EP Impurity A used for?

Capecitabine EP Impurity A is supplied as a characterised reference material related to Capecitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Capecitabine EP Impurity A can I order?

We supply Capecitabine EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Capecitabine EP Impurity A?

Yes. Every lot of Capecitabine EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Capecitabine EP Impurity A be shipped internationally?

Yes. Capecitabine EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.