Hydrocortisone 21-Propionate

About Hydrocortisone 21-Propionate

Hydrocortisone 21-Propionate is an impurity of Hydrocortisone carrying the CAS registry number 6677-98-1. The compound has the formula C24H34O6, corresponding to a molecular weight of 418.5 g/mol. Alternative names: Hydrocortisone propionate and Cortisol, 21-propionate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Hydrocortisone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Hydrocortisone 21-Propionate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Hydrocortisone

View every impurity, metabolite and intermediate we list for Hydrocortisone.

Hydrocortisone impurities

Specifications & identifiers

Chemical identifiers
Product name	Hydrocortisone 21-Propionate
Catalogue No.	VQ-022806
CAS Number	6677-98-1
IUPAC name	[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
Molecular formula	C₂₄H₃₄O₆
Molecular weight	418.5 g/mol
Exact mass	418.2355
Grade	Reference Standard
HSN code	38229090
InChIKey	MRECAIZOMKKXOZ-RPPPWEFESA-N
SMILES	CCC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)O
PubChem CID	111228

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	2 / 6
TPSA	101 Å²
Synonyms	Hydrocortisone propionate, Cortisol, 21-propionate, 11,17-Dihydroxy-21-(1-oxopropoxy)pregn-4-ene-3,20-dione (11beta)-, 11beta,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl propanoate, Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-(1-oxopropoxy)-, (11beta)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydrocortisone 21-Propionate?

The CAS Registry Number of Hydrocortisone 21-Propionate is 6677-98-1. It is also known as Hydrocortisone propionate, Cortisol, 21-propionate, 11,17-Dihydroxy-21-(1-oxopropoxy)pregn-4-ene-3,20-dione (11beta)-.

What is the molecular formula and molecular weight of Hydrocortisone 21-Propionate?

Hydrocortisone 21-Propionate has the molecular formula C24H34O6 and a molecular weight of 418.5 g/mol.

What is Hydrocortisone 21-Propionate used for?

Hydrocortisone 21-Propionate is supplied as a characterised reference material related to Hydrocortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydrocortisone 21-Propionate can I order?

We supply Hydrocortisone 21-Propionate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydrocortisone 21-Propionate?

Yes. Every lot of Hydrocortisone 21-Propionate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydrocortisone 21-Propionate be shipped internationally?

Yes. We export Hydrocortisone 21-Propionate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.