Isotretinoin EP Impurity H

Name: Isotretinoin EP Impurity H
Brand: Vaqora Chemicals
SKU: VQ-022871

About Isotretinoin EP Impurity H

Vaqora Chemicals supplies Isotretinoin EP Impurity H, a pharmacopeial impurity of Isotretinoin registered under CAS number 71748-58-8. With the molecular formula C20H26O3, it has a molar mass of 314.4 g/mol. Systematically, it is named (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid. Alternative names: Isotretinoin EP Impurity H (Free Base) and 4-Keto 13-cis-Retinoic Acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Isotretinoin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Isotretinoin EP Impurity H is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Isotretinoin

View every impurity, metabolite and intermediate we list for Isotretinoin.

Isotretinoin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Isotretinoin EP Impurity H
Catalogue No.	VQ-022871
CAS Number	71748-58-8
IUPAC name	(2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
Molecular formula	C₂₀H₂₆O₃
Molecular weight	314.4 g/mol
Exact mass	314.1882
Grade	Reference Standard
HSN code	38229090
InChIKey	GGCUJPCCTQNTJF-FAOQNJJDSA-N
SMILES	CC1=C(C(CCC1=O)(C)C)/C=C/C(=C/C=C/C(=C\C(=O)O)/C)/C
PubChem CID	6437087

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	1 / 3
TPSA	54.4 Å²
Synonyms	Isotretinoin EP Impurity H (Free Base), 4-Keto 13-cis-Retinoic Acid, Isotretinoin - Impurity H, 4-Oxoisotretinoin, 13-cis-4-Oxoretinoic acid, Oxoretinoic acid, 4-Oxo-13-cis retinoic acid, Retinoic acid, 4-oxo-, 13-cis-, 4-Oxo-13-cis-retinoic acid, 4-Oxo-isotretinoin, Isotretinoin impurity H, EX-A914

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H360May damage fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Isotretinoin EP Impurity H?

The CAS Registry Number of Isotretinoin EP Impurity H is 71748-58-8. It is also known as Isotretinoin EP Impurity H (Free Base), 4-Keto 13-cis-Retinoic Acid, Isotretinoin - Impurity H.

What is the molecular formula and molecular weight of Isotretinoin EP Impurity H?

Isotretinoin EP Impurity H has the molecular formula C20H26O3 and a molecular weight of 314.4 g/mol. Its IUPAC name is (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid.

What is Isotretinoin EP Impurity H used for?

Isotretinoin EP Impurity H is supplied as a characterised reference material related to Isotretinoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Isotretinoin EP Impurity H can I order?

We supply Isotretinoin EP Impurity H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isotretinoin EP Impurity H?

Yes. Every lot of Isotretinoin EP Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isotretinoin EP Impurity H be shipped internationally?

Yes. Isotretinoin EP Impurity H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.