(6R)-Folinic Acid

Name: (6R)-Folinic Acid
Brand: Vaqora Chemicals
SKU: VQ-025897

About (6R)-Folinic Acid

(6R)-Folinic Acid (CAS 73951-54-9) is an impurity of Levofolinate offered by Vaqora Chemicals. With the molecular formula C20H23N7O7, it has a molar mass of 473.4 g/mol. Common synonyms include 6R-Leucovorin and (6R)-5-Formyl-5,6,7,8-tetrahydrofolic acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Levofolinate, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (6R)-Folinic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Levofolinate

View every impurity, metabolite and intermediate we list for Levofolinate.

Levofolinate impurities

Specifications & identifiers

Chemical identifiers
Product name	(6R)-Folinic Acid
Catalogue No.	VQ-025897
CAS Number	73951-54-9
IUPAC name	(2S)-2-[[4-[[(6R)-2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid
Molecular formula	C₂₀H₂₃N₇O₇
Molecular weight	473.4 g/mol
Exact mass	473.1659
Grade	Reference Standard
HSN code	38229090
InChIKey	VVIAGPKUTFNRDU-OLZOCXBDSA-N
SMILES	C1[C@H](N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	135484651

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.2
H-bond donors / acceptors	7 / 10
TPSA	216 Å²
Synonyms	6R-Leucovorin, (6R)-5-Formyl-5,6,7,8-tetrahydrofolic acid, [6R]-5-formyl-5,6,7,8-tetrahydrofolate, (6R)-5-formyl-5,6,7,8-tetrahydrofolate, (6R)-Leucovorin, Dextrofolinic acid, (6R,2'S)-Folinic acid, Folinic acid, (6R)-, (6r,s)-5-formyltetrahydrofolic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (6R)-Folinic Acid?

The CAS Registry Number of (6R)-Folinic Acid is 73951-54-9. It is also known as 6R-Leucovorin, (6R)-5-Formyl-5,6,7,8-tetrahydrofolic acid, [6R]-5-formyl-5,6,7,8-tetrahydrofolate.

What is the molecular formula and molecular weight of (6R)-Folinic Acid?

(6R)-Folinic Acid has the molecular formula C20H23N7O7 and a molecular weight of 473.4 g/mol. Its IUPAC name is (2S)-2-[[4-[[(6R)-2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid.

What is (6R)-Folinic Acid used for?

(6R)-Folinic Acid is supplied as a characterised reference material related to Levofolinate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (6R)-Folinic Acid can I order?

We supply (6R)-Folinic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (6R)-Folinic Acid?

Yes. Every lot of (6R)-Folinic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (6R)-Folinic Acid be shipped internationally?

Yes. We export (6R)-Folinic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.