17beta-Carboxy-17-desoxy dexamethasone

Name: 17beta-Carboxy-17-desoxy dexamethasone
Brand: Vaqora Chemicals
SKU: VQ-022338

About 17beta-Carboxy-17-desoxy dexamethasone

Vaqora Chemicals supplies 17beta-Carboxy-17-desoxy dexamethasone, an impurity of Dexamethasone registered under CAS number 75262-69-0. Its molecular formula is C21H27FO4 and its molecular weight is 362.4 g/mol. Common synonyms include 17β-Carboxy-17-desoxy Dexamethasone and Desoximetasone Acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Dexamethasone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 17beta-Carboxy-17-desoxy dexamethasone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dexamethasone

View every impurity, metabolite and intermediate we list for Dexamethasone.

Dexamethasone impurities

Specifications & identifiers

Chemical identifiers
Product name	17beta-Carboxy-17-desoxy dexamethasone
Catalogue No.	VQ-022338
CAS Number	75262-69-0
IUPAC name	(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylic acid
Molecular formula	C₂₁H₂₇FO₄
Molecular weight	362.4 g/mol
Exact mass	362.1893
Grade	Reference Standard
HSN code	38229090
InChIKey	VNEWQJPVNZRHHG-MIESIBRYSA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@H]1C(=O)O)C)O)F)C
PubChem CID	57660981

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	2 / 5
TPSA	74.6 Å²
Synonyms	17β-Carboxy-17-desoxy Dexamethasone, Desoximetasone Acid, 9-Fluoro-11beta-hydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta-carboxylic acid, (11, A,16, A,17, A)-9-Fluoro-11-hydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic Acid

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P319, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 17beta-Carboxy-17-desoxy dexamethasone?

The CAS Registry Number of 17beta-Carboxy-17-desoxy dexamethasone is 75262-69-0. It is also known as 17β-Carboxy-17-desoxy Dexamethasone, Desoximetasone Acid, 9-Fluoro-11beta-hydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta-carboxylic acid.

What is the molecular formula and molecular weight of 17beta-Carboxy-17-desoxy dexamethasone?

17beta-Carboxy-17-desoxy dexamethasone has the molecular formula C21H27FO4 and a molecular weight of 362.4 g/mol. Its IUPAC name is (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylic acid.

What is 17beta-Carboxy-17-desoxy dexamethasone used for?

17beta-Carboxy-17-desoxy dexamethasone is supplied as a characterised reference material related to Dexamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 17beta-Carboxy-17-desoxy dexamethasone can I order?

We supply 17beta-Carboxy-17-desoxy dexamethasone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 17beta-Carboxy-17-desoxy dexamethasone?

Yes. Every lot of 17beta-Carboxy-17-desoxy dexamethasone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 17beta-Carboxy-17-desoxy dexamethasone be shipped internationally?

Yes. 17beta-Carboxy-17-desoxy dexamethasone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.