Sitagliptin Triazole Hydrochloride

Name: Sitagliptin Triazole Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-013798

About Sitagliptin Triazole Hydrochloride

Sitagliptin Triazole Hydrochloride (CAS 762240-92-6) is a process intermediate or related compound of Sitagliptin offered by Vaqora Chemicals. Formula C6H8ClF3N4, molecular weight 228.6 g/mol. Its systematic (IUPAC) name is 3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine. Hydrochloride. It is also known as 2,5-Bis(trifluoromethyl)bromobenzene or 3-(Trifluoromethyl).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Sitagliptin, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sitagliptin Triazole Hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin Triazole Hydrochloride
Catalogue No.	VQ-013798
CAS Number	762240-92-6
Other CAS	486460-21-3
IUPAC name	3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine;hydrochloride
Molecular formula	C₆H₈ClF₃N₄
Molecular weight	228.6 g/mol
Exact mass	228.039
Grade	Reference Standard
HSN code	2933
InChIKey	AQCSCRYRCRORET-UHFFFAOYSA-N
SMILES	C1CN2C(=NN=C2C(F)(F)F)CN1.Cl
PubChem CID	11961371

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 6
TPSA	42.7 Å²
Synonyms	3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride, 2,5-Bis(trifluoromethyl)bromobenzene, 5,6,7,8-Tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine Monohydrochloride, 3-(Trifluoromethyl)-5,6,7,8-tetrahydro(1,2,4)triazolo(4,3-a)pyrazine hydrochloride (1:1), 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-(1,2,4)triazolo(4,3-a)pyrazine hydrochloride, 3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine hydrochloride (1:1), 3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride, 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine hydrochloride, 3-(Trifluoromethyl), 3-trifluoromethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride, 3-Trifluoromethyl-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a]pyrazine hydrochloride, 3-(Trifluoromethyl)-1,2,4-triazolo[4,3-a]piperazine Hydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sitagliptin Triazole Hydrochloride?

The CAS Registry Number of Sitagliptin Triazole Hydrochloride is 762240-92-6. It is also known as 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride, 2,5-Bis(trifluoromethyl)bromobenzene, 5,6,7,8-Tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine Monohydrochloride.

What is the molecular formula and molecular weight of Sitagliptin Triazole Hydrochloride?

Sitagliptin Triazole Hydrochloride has the molecular formula C6H8ClF3N4 and a molecular weight of 228.6 g/mol.

What is Sitagliptin Triazole Hydrochloride used for?

Sitagliptin Triazole Hydrochloride is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin Triazole Hydrochloride can I order?

We supply Sitagliptin Triazole Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin Triazole Hydrochloride?

Yes. Every lot of Sitagliptin Triazole Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin Triazole Hydrochloride be shipped internationally?

Yes. Sitagliptin Triazole Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.