Sitagliptin Ketoamide Impurity

Name: Sitagliptin Ketoamide Impurity
Brand: Vaqora Chemicals
SKU: VQ-005934

About Sitagliptin Ketoamide Impurity

Listed under CAS 764667-65-4, Sitagliptin Ketoamide Impurity is an impurity of Sitagliptin available from Vaqora Chemicals, specified at 54.93% purity. Its molecular formula is C16H12F6N4O2 and its molecular weight is 406.28 g/mol. Common synonyms include Sitagliptin Ketoamide and rac-Sitagliptin 3-ketone.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Sitagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sitagliptin Ketoamide Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin Ketoamide Impurity
Catalogue No.	VQ-005934
CAS Number	764667-65-4
IUPAC name	1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione
Molecular formula	C₁₆H₁₂F₆N₄O₂
Molecular weight	406.28 g/mol
Exact mass	406.0864
Grade	Reference Standard
Purity / assay	54.93%
HSN code	38229090
InChIKey	QAEDTLFWHIEVPK-UHFFFAOYSA-N
SMILES	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)CC(=O)CC3=CC(=C(C=C3F)F)F
PubChem CID	9887588

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	0 / 10
TPSA	68.1 Å²
Synonyms	Sitagliptin Ketoamide, rac-Sitagliptin 3-ketone, Prositagliptin ketone, Sitagliptin Impurity 13, Sitagliptin keto amide, Sitagliptin Impurity J, -1-(2,4,5-trifluorophenyl)butan-2-one, 4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sitagliptin Ketoamide Impurity?

The CAS Registry Number of Sitagliptin Ketoamide Impurity is 764667-65-4. It is also known as Sitagliptin Ketoamide, rac-Sitagliptin 3-ketone, Prositagliptin ketone.

What is the molecular formula and molecular weight of Sitagliptin Ketoamide Impurity?

Sitagliptin Ketoamide Impurity has the molecular formula C16H12F6N4O2 and a molecular weight of 406.28 g/mol. Its IUPAC name is 1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione.

What is Sitagliptin Ketoamide Impurity used for?

Sitagliptin Ketoamide Impurity is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin Ketoamide Impurity can I order?

We supply Sitagliptin Ketoamide Impurity in Reference Standard (54.93%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin Ketoamide Impurity?

Yes. Every lot of Sitagliptin Ketoamide Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin Ketoamide Impurity be shipped internationally?

Yes. We export Sitagliptin Ketoamide Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.