Calcium Levofolinate

Name: Calcium Levofolinate
Brand: Vaqora Chemicals
SKU: VQ-037394

About Calcium Levofolinate

Vaqora Chemicals supplies Calcium Levofolinate, a high-purity reference standard of Levofolinate registered under CAS number 80433-71-2. Formula C20H21CaN7O7, molecular weight 511.5 g/mol. It is also known as Calcium Levofolinate Pentahydrate or Elvorine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Levofolinate standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Levofolinate

View every impurity, metabolite and intermediate we list for Levofolinate.

Levofolinate impurities

Specifications & identifiers

Chemical identifiers
Product name	Calcium Levofolinate
Catalogue No.	VQ-037394
CAS Number	80433-71-2
IUPAC name	calcium (2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate
Molecular formula	C₂₀H₂₁CaN₇O₇
Molecular weight	511.5 g/mol
Exact mass	511.1128
Grade	Reference Standard
HSN code	38229090
InChIKey	KVUAALJSMIVURS-QNTKWALQSA-L
SMILES	C1[C@@H](N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Ca+2]
PubChem CID	135500522

Physical properties
Physical form	Solid
H-bond donors / acceptors	5 / 10
TPSA	221 Å²
Synonyms	Calcium Levofolinate Pentahydrate, Elvorine, Calcium levofolinate (6s,l), Folinic acid l-form calcium salt, calcium levoleucovorin, levoleucovorin injection, Isovorin, L-Leucovorin calcium, calcium (6s)-folinate, Levofolinate calcium, Calcium levofolinate (Calcium Folinate), Levofolinate calcium (JAN)

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P261, P271, P272, P280, P284, P302 + P352, P304 + P340, P321, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Calcium Levofolinate?

The CAS Registry Number of Calcium Levofolinate is 80433-71-2. It is also known as Calcium Levofolinate Pentahydrate, Elvorine, Calcium levofolinate (6s,l).

What is the molecular formula and molecular weight of Calcium Levofolinate?

Calcium Levofolinate has the molecular formula C20H21CaN7O7 and a molecular weight of 511.5 g/mol. Its IUPAC name is calcium (2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate.

What is Calcium Levofolinate used for?

Calcium Levofolinate is supplied as a characterised reference material related to Levofolinate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Calcium Levofolinate can I order?

We supply Calcium Levofolinate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Calcium Levofolinate?

Yes. Every lot of Calcium Levofolinate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Calcium Levofolinate be shipped internationally?

Yes. Calcium Levofolinate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.