2-Hydroxy Estrone-D4

Name: 2-Hydroxy Estrone-D4
Brand: Vaqora Chemicals
SKU: VQ-048281

About 2-Hydroxy Estrone-D4

Vaqora Chemicals supplies 2-Hydroxy Estrone-D4, a stable isotope labelled analogue related to Estrone registered under CAS number 81586-97-2. With the molecular formula C18H22O3, it has a molar mass of 290.4 g/mol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Estrone and related analytes in bioanalytical, pharmacokinetic and impurity studies. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Estrone

View every impurity, metabolite and intermediate we list for Estrone.

Estrone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	2-Hydroxy Estrone-D4
Catalogue No.	VQ-048281
CAS Number	81586-97-2
IUPAC name	(8R,9S,13S,14S)-1,4,16,16-tetradeuterio-2,3-dihydroxy-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-17-one
Molecular formula	C₁₈H₂₂O₃
Molecular weight	290.4 g/mol
Exact mass	290.182
Grade	Reference Standard
HSN code	38229090
InChIKey	SWINWPBPEKHUOD-PJZZMCTGSA-N
SMILES	[2H]C1=C2CC[C@@H]3[C@@H](C2=C(C(=C1O)O)[2H])CC[C@]4([C@H]3CC(C4=O)([2H])[2H])C
PubChem CID	71749016

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	2 / 3
TPSA	57.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Hydroxy Estrone-D4?

The CAS Registry Number of 2-Hydroxy Estrone-D4 is 81586-97-2. It is also known as 2,3-Dihydroxy(1,4,16,16-~2~H_4_)estra-1(10),2,4-trien-17-one.

What is the molecular formula and molecular weight of 2-Hydroxy Estrone-D4?

2-Hydroxy Estrone-D4 has the molecular formula C18H22O3 and a molecular weight of 290.4 g/mol. Its IUPAC name is (8R,9S,13S,14S)-1,4,16,16-tetradeuterio-2,3-dihydroxy-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-17-one.

What is 2-Hydroxy Estrone-D4 used for?

2-Hydroxy Estrone-D4 is supplied as a characterised reference material related to Estrone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Hydroxy Estrone-D4 can I order?

We supply 2-Hydroxy Estrone-D4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Hydroxy Estrone-D4?

Yes. Every lot of 2-Hydroxy Estrone-D4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Hydroxy Estrone-D4 be shipped internationally?

Yes. We export 2-Hydroxy Estrone-D4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.