Ketoconazole EP Impurity C

Name: Ketoconazole EP Impurity C
Brand: Vaqora Chemicals
SKU: VQ-031368

About Ketoconazole EP Impurity C

Ketoconazole EP Impurity C (CAS 83374-59-8) is a pharmacopeial impurity of Ketoconazole offered by Vaqora Chemicals. Formula C26H28Cl2N4O4, molecular weight 531.4 g/mol. Common synonyms include Ketoconazole Impurity C and Ketoconazole - Impurity C.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Ketoconazole impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Ketoconazole EP Impurity C in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Ketoconazole

View every impurity, metabolite and intermediate we list for Ketoconazole.

Ketoconazole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ketoconazole EP Impurity C
Catalogue No.	VQ-031368
CAS Number	83374-59-8
IUPAC name	1-[4-[4-[[(2R,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
Molecular formula	C₂₆H₂₈Cl₂N₄O₄
Molecular weight	531.4 g/mol
Exact mass	530.1488
Grade	Reference Standard
HSN code	38229090
InChIKey	XMAYWYJOQHXEEK-BVAGGSTKSA-N
SMILES	CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OC[C@@H]3CO[C@](O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
PubChem CID	12854713

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	0 / 6
TPSA	69.1 Å²
Synonyms	Ketoconazole Impurity C, Ketoconazole - Impurity C, trans-Ketoconazole, Ketoconazole, trans-, rac-trans-Ketoconazole, (2R,4R)-ketoconazole, Ketoconazole, trans-(+/-)-, (2R,4R)-trans-Ketoconazole, Ketoconazole Impurity 60, Ketoconazole, (2R,4R)-

Safety & hazard information (GHS)

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P316, P318, P319, P321, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ketoconazole EP Impurity C?

The CAS Registry Number of Ketoconazole EP Impurity C is 83374-59-8. It is also known as Ketoconazole Impurity C, Ketoconazole - Impurity C, trans-Ketoconazole.

What is the molecular formula and molecular weight of Ketoconazole EP Impurity C?

Ketoconazole EP Impurity C has the molecular formula C26H28Cl2N4O4 and a molecular weight of 531.4 g/mol. Its IUPAC name is 1-[4-[4-[[(2R,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone.

What is Ketoconazole EP Impurity C used for?

Ketoconazole EP Impurity C is supplied as a characterised reference material related to Ketoconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ketoconazole EP Impurity C can I order?

We supply Ketoconazole EP Impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ketoconazole EP Impurity C?

Yes. Every lot of Ketoconazole EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ketoconazole EP Impurity C be shipped internationally?

Yes. Ketoconazole EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.