Sofosbuvir Nucleoside Derivative

About Sofosbuvir Nucleoside Derivative

Sofosbuvir Nucleoside Derivative is a metabolite or degradation product of Sofosbuvir carrying the CAS registry number 863329-66-2. With the molecular formula C10H13FN2O5, it has a molar mass of 260.22 g/mol. Systematically, it is named 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione. Alternative names: Sofosbuvir metabolite GS331007 and PSI-6206.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Sofosbuvir, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Sofosbuvir Nucleoside Derivative in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Sofosbuvir

View every impurity, metabolite and intermediate we list for Sofosbuvir.

Sofosbuvir impurities

Specifications & identifiers

Chemical identifiers
Product name	Sofosbuvir Nucleoside Derivative
Catalogue No.	VQ-023774
CAS Number	863329-66-2
IUPAC name	1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione
Molecular formula	C₁₀H₁₃FN₂O₅
Molecular weight	260.22 g/mol
Exact mass	260.0808
Grade	Reference Standard
HSN code	38229090
InChIKey	ARKKGZQTGXJVKW-VPCXQMTMSA-N
SMILES	C[C@]1([C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CO)O)F
PubChem CID	11311503

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.1
H-bond donors / acceptors	3 / 6
TPSA	99.1 Å²
Synonyms	Sofosbuvir metabolite GS331007, PSI-6206, (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine, Uridine, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)-, 2'-Deoxy-2'-fluoro-2'-C-methyluridine, (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-uridine, 2'-deoxy-2'-fluoro-2'-methyluridine, Sofosbuvir Metabolites GS331007, EX-A2144, 2'-deoxy-2'-fluoro-2'-C-methyl-uridine, (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine / PSI-6206

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sofosbuvir Nucleoside Derivative?

The CAS Registry Number of Sofosbuvir Nucleoside Derivative is 863329-66-2. It is also known as Sofosbuvir metabolite GS331007, PSI-6206, (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine.

What is the molecular formula and molecular weight of Sofosbuvir Nucleoside Derivative?

Sofosbuvir Nucleoside Derivative has the molecular formula C10H13FN2O5 and a molecular weight of 260.22 g/mol. Its IUPAC name is 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione.

What is Sofosbuvir Nucleoside Derivative used for?

Sofosbuvir Nucleoside Derivative is supplied as a characterised reference material related to Sofosbuvir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sofosbuvir Nucleoside Derivative can I order?

We supply Sofosbuvir Nucleoside Derivative in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sofosbuvir Nucleoside Derivative?

Yes. Every lot of Sofosbuvir Nucleoside Derivative is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sofosbuvir Nucleoside Derivative be shipped internationally?

Yes. Sofosbuvir Nucleoside Derivative is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.