Irinotecan EP Impurity E

Name: Irinotecan EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-021241

About Irinotecan EP Impurity E

Vaqora Chemicals supplies Irinotecan EP Impurity E, a pharmacopeial impurity of Camptothecin registered under CAS number 86639-52-3. The compound has the formula C22H20N2O5, corresponding to a molecular weight of 392.4 g/mol. Common synonyms include 7-Ethyl-10-Hydroxycamptothecin and Camptothecin 7-ethyl-10-hydroxy Impurity.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Camptothecin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Irinotecan EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Camptothecin

View every impurity, metabolite and intermediate we list for Camptothecin.

Camptothecin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Irinotecan EP Impurity E
Catalogue No.	VQ-021241
CAS Number	86639-52-3
IUPAC name	(19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
Molecular formula	C₂₂H₂₀N₂O₅
Molecular weight	392.4 g/mol
Exact mass	392.1372
Grade	Reference Standard
HSN code	38229090
InChIKey	FJHBVJOVLFPMQE-QFIPXVFZSA-N
SMILES	CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)O
PubChem CID	104842

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	2 / 6
TPSA	100 Å²
Synonyms	7-Ethyl-10-Hydroxycamptothecin, Camptothecin 7-ethyl-10-hydroxy Impurity, Irinotecan - Impurity E, Irinotecan Related Compound B, SN-38, SN 38, 10-Hydroxy-7-ethylcamptothecin, NK-012, 7-Ethyl-10-hydroxy-20(S)-camptothecin, NK 012

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H341Suspected of causing genetic defects

Precautionary statements: P203, P264, P270, P280, P301 + P316, P318, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Irinotecan EP Impurity E?

The CAS Registry Number of Irinotecan EP Impurity E is 86639-52-3. It is also known as 7-Ethyl-10-Hydroxycamptothecin, Camptothecin 7-ethyl-10-hydroxy Impurity, Irinotecan - Impurity E.

What is the molecular formula and molecular weight of Irinotecan EP Impurity E?

Irinotecan EP Impurity E has the molecular formula C22H20N2O5 and a molecular weight of 392.4 g/mol. Its IUPAC name is (19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione.

What is Irinotecan EP Impurity E used for?

Irinotecan EP Impurity E is supplied as a characterised reference material related to Camptothecin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Irinotecan EP Impurity E can I order?

We supply Irinotecan EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Irinotecan EP Impurity E?

Yes. Every lot of Irinotecan EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Irinotecan EP Impurity E be shipped internationally?

Yes. Irinotecan EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.