Rac Crizotinib

Name: Rac Crizotinib
Brand: Vaqora Chemicals
SKU: VQ-036448

About Rac Crizotinib

Vaqora Chemicals supplies Rac Crizotinib, an impurity of Crizotinib registered under CAS number 877400-66-3. The compound has the formula C21H22Cl2FN5O, corresponding to a molecular weight of 450.3 g/mol. Its systematic (IUPAC) name is 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine. It is also known as (R,S)-Crizotinib or Crizotinib Racemic Mixture.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Crizotinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Rac Crizotinib in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Crizotinib

View every impurity, metabolite and intermediate we list for Crizotinib.

Crizotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Rac Crizotinib
Catalogue No.	VQ-036448
CAS Number	877400-66-3
IUPAC name	3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine
Molecular formula	C₂₁H₂₂Cl₂FN₅O
Molecular weight	450.3 g/mol
Exact mass	449.1185
Grade	Reference Standard
HSN code	38229090
InChIKey	KTEIFNKAUNYNJU-UHFFFAOYSA-N
SMILES	CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N
PubChem CID	11597571

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	2 / 6
TPSA	78 Å²
Synonyms	(R,S)-Crizotinib, Crizotinib Racemic Mixture, racemic crizotinib, (+-)-crizotinib, Kinome_3143, Kinome_3144, Kinome_3145, Crizotinib, (R,S)-, 3-[1-(2,6-dichloro-3-fluoro-phenyl)ethoxy]-5-[1-(4-piperidyl)pyrazol-4-yl]pyridin-2-amine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rac Crizotinib?

The CAS Registry Number of Rac Crizotinib is 877400-66-3. It is also known as (R,S)-Crizotinib, Crizotinib Racemic Mixture, racemic crizotinib.

What is the molecular formula and molecular weight of Rac Crizotinib?

Rac Crizotinib has the molecular formula C21H22Cl2FN5O and a molecular weight of 450.3 g/mol. Its IUPAC name is 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine.

What is Rac Crizotinib used for?

Rac Crizotinib is supplied as a characterised reference material related to Crizotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rac Crizotinib can I order?

We supply Rac Crizotinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rac Crizotinib?

Yes. Every lot of Rac Crizotinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rac Crizotinib be shipped internationally?

Yes. We export Rac Crizotinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.