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Ireland![N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure](/media/structures/GWMBPMUFLFJILW-BWKNWUBXSA-N.svg)
N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- CAS
- 923036-30-0
- Formula
- C27H31N5O2S
- MW
- 489.6 g/mol
VQ-028420
VAQORA2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine
Synonyms: 2,4-dichloro-1H-pyrrolo[2,3-d]pyrimidine · 2,6-Dichloro-7-deazapurine · 2,4-dichloropyrrolo[2,3-d]pyrimidine · 1H-Pyrrolo[2,3-d]pyrimidine, 2,4-dichloro-
CAS No.90213-66-4
FormulaC6H3Cl2N3
Mol. weight188.01
Catalogue No.VQ-028421
PurityReference Standard
HSN38229090
2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine (CAS 90213-66-4) – Tofacitinib impurity standard. C6H3Cl2N3, MW 188.01. Vaqora Chemicals: COA, global shipping.
Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
Enquire Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing
About 2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine
2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine is an impurity of Tofacitinib carrying the CAS registry number 90213-66-4. With the molecular formula C6H3Cl2N3, it has a molar mass of 188.01 g/mol. Alternative names: 2,4-dichloro-1H-pyrrolo[2,3-d]pyrimidine and 2,6-Dichloro-7-deazapurine.
The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.
This Tofacitinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.
Vaqora Chemicals supplies 2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
Related to Tofacitinib
View every impurity, metabolite and intermediate we list for Tofacitinib.
Tofacitinib impuritiesSpecifications & identifiers
| Product name | 2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine |
|---|---|
| Catalogue No. | VQ-028421 |
| CAS Number | 90213-66-4 |
| IUPAC name | 2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine |
| Molecular formula | C6H3Cl2N3 |
| Molecular weight | 188.01 g/mol |
| Exact mass | 186.9704 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | GHXBPCSSQOKKGB-UHFFFAOYSA-N |
| SMILES | C1=CNC2=C1C(=NC(=N2)Cl)Cl |
| PubChem CID | 14116871 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 2.6 |
| H-bond donors / acceptors | 1 / 2 |
| TPSA | 41.6 Ų |
| Synonyms | 2,4-dichloro-1H-pyrrolo[2,3-d]pyrimidine, 2,6-Dichloro-7-deazapurine, 2,4-dichloropyrrolo[2,3-d]pyrimidine, 1H-Pyrrolo[2,3-d]pyrimidine, 2,4-dichloro-, CS-B0455, 7H-2,4-dichloro-pyrrolo[2,3-d]pyrimidine, 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine, AldrichCPR |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H301Toxic if swallowedH302Harmful if swallowedH315Causes skin irritationH319Causes serious eye irritationH335May cause respiratory irritation
Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of 2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine?
The CAS Registry Number of 2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine is 90213-66-4. It is also known as 2,4-dichloro-1H-pyrrolo[2,3-d]pyrimidine, 2,6-Dichloro-7-deazapurine, 2,4-dichloropyrrolo[2,3-d]pyrimidine.
What is the molecular formula and molecular weight of 2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine?
2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine has the molecular formula C6H3Cl2N3 and a molecular weight of 188.01 g/mol. Its IUPAC name is 2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine.
What is 2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine used for?
2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine is supplied as a characterised reference material related to Tofacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of 2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine can I order?
We supply 2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with 2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine?
Yes. Every lot of 2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can 2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine be shipped internationally?
Yes. 2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about 2,4-Dichloro-7H-Pyrrolo (2,3-d)Pyrimidine
We reply within one business day with price, pack options, lead time and documentation.
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