(1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-… 905454-58-2

About (1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane

(1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane is an impurity of Nebivolol carrying the CAS registry number 905454-58-2. With the molecular formula C18H19FO5S, it has a molar mass of 366.4 g/mol. Systematically, it is named [(2S)-2-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl] 4-methylbenzenesulfonate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Nebivolol, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer (1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nebivolol

View every impurity, metabolite and intermediate we list for Nebivolol.

Nebivolol impurities

Specifications & identifiers

Chemical identifiers
Product name	(1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane
Catalogue No.	VQ-032080
CAS Number	905454-58-2
IUPAC name	[(2S)-2-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl] 4-methylbenzenesulfonate
Molecular formula	C₁₈H₁₉FO₅S
Molecular weight	366.4 g/mol
Exact mass	366.0937
Grade	Reference Standard
HSN code	38229090
InChIKey	SRYHEPKRXGABEM-WMZOPIPTSA-N
SMILES	CC1=CC=C(C=C1)S(=O)(=O)OC[C@@H]([C@@H]2CCC3=C(O2)C=CC(=C3)F)O
PubChem CID	71752638

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	1 / 6
TPSA	81.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane?

The CAS Registry Number of (1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane is 905454-58-2. It is also known as (S)-2-((S)-6-Fluorochroman-2-yl)-2-hydroxyethyl 4-methylbenzenesulfonate.

What is the molecular formula and molecular weight of (1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane?

(1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane has the molecular formula C18H19FO5S and a molecular weight of 366.4 g/mol. Its IUPAC name is [(2S)-2-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl] 4-methylbenzenesulfonate.

What is (1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane used for?

(1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane is supplied as a characterised reference material related to Nebivolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane can I order?

We supply (1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane?

Yes. Every lot of (1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane be shipped internationally?

Yes. We export (1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.