Levothyroxine EP Impurity F

Name: Levothyroxine EP Impurity F
Brand: Vaqora Chemicals
SKU: VQ-006475

About Levothyroxine EP Impurity F

Levothyroxine EP Impurity F is a pharmacopeial impurity of Levothyroxine carrying the CAS registry number 911661-90-0. The compound has the formula C21H13I6NO5, corresponding to a molecular weight of 1120.8 g/mol. Systematically, it is named (2S)-2-amino-3-[4-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenoxy]-3,5-diiodophenyl]propanoic acid. Common synonyms include Thyroxine-4-hydroxy-3,5-diiodophenyl Ether and O-(4-Hydroxy-3,5-diiodophenyl)thyroxine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Levothyroxine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Levothyroxine EP Impurity F in 10 mg, 25 mg and 50 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Levothyroxine EP Impurity F
Catalogue No.	VQ-006475
CAS Number	911661-90-0
IUPAC name	(2S)-2-amino-3-[4-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenoxy]-3,5-diiodophenyl]propanoic acid
Molecular formula	C₂₁H₁₃I₆NO₅
Molecular weight	1120.8 g/mol
Exact mass	1120.5062
Grade	Reference Standard
HSN code	38229090
InChIKey	DBVHFBLWQRLBJN-KRWDZBQOSA-N
SMILES	C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)OC3=CC(=C(C(=C3)I)O)I)I)I)C[C@@H](C(=O)O)N
PubChem CID	71433959

Physical properties
Physical form	Solid
LogP (XLogP3)	5.2
H-bond donors / acceptors	3 / 6
TPSA	102 Å²
Synonyms	Thyroxine-4-hydroxy-3,5-diiodophenyl Ether, O-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-3,5-diiodo-L-tyrosine, β-[4-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenoxy]-3,5-diiodophenyl]alanine, O-(4-Hydroxy-3,5-diiodophenyl)thyroxine, L-Tyrosine, O-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-3,5-diiodo-, Alanine, beta-(4-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenoxy)-3,5-diiodophenyl)-, Levothyroxine sodium impurity, O-(4-hydroxy-3,5-diiodophenyl)thyroxine, or T6-(USP), Levothyroxine sodium specified impurity F

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levothyroxine EP Impurity F?

The CAS Registry Number of Levothyroxine EP Impurity F is 911661-90-0. It is also known as Thyroxine-4-hydroxy-3,5-diiodophenyl Ether, O-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-3,5-diiodo-L-tyrosine, β-[4-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenoxy]-3,5-diiodophenyl]alanine.

What is the molecular formula and molecular weight of Levothyroxine EP Impurity F?

Levothyroxine EP Impurity F has the molecular formula C21H13I6NO5 and a molecular weight of 1120.8 g/mol. Its IUPAC name is (2S)-2-amino-3-[4-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenoxy]-3,5-diiodophenyl]propanoic acid.

What is Levothyroxine EP Impurity F used for?

Levothyroxine EP Impurity F is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine EP Impurity F can I order?

We supply Levothyroxine EP Impurity F in Reference Standard grade, in 10 mg, 25 mg, 50 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine EP Impurity F?

Yes. Every lot of Levothyroxine EP Impurity F is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine EP Impurity F be shipped internationally?

Yes. We export Levothyroxine EP Impurity F worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.