Neratinib Maleate

Name: Neratinib Maleate
Brand: Vaqora Chemicals
SKU: VQ-007608

About Neratinib Maleate

Vaqora Chemicals supplies Neratinib Maleate, a high-purity reference standard of Neratinib registered under CAS number 915942-22-2. Its molecular formula is C34H33ClN6O7 and its molecular weight is 673.1 g/mol. It is also known as Nerlynx or hki-272 maleate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Neratinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Neratinib Maleate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Neratinib

View every impurity, metabolite and intermediate we list for Neratinib.

Neratinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Neratinib Maleate
Catalogue No.	VQ-007608
CAS Number	915942-22-2
Other CAS	698387-09-6
IUPAC name	(Z)-but-2-enedioic acid;(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
Molecular formula	C₃₄H₃₃ClN₆O₇
Molecular weight	673.1 g/mol
Exact mass	672.2099
Grade	Reference Standard
HSN code	38229090
InChIKey	VXZCUHNJXSIJIM-MEBGWEOYSA-N
SMILES	CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C.C(=C\C(=O)O)\C(=O)O
PubChem CID	67307512

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 12
TPSA	187 Å²
Synonyms	Nerlynx, hki-272 maleate, Neratinib (maleate), C34H33ClN6O7, 915942-22-2 (maleate), Nerlynx (TN), Neratinib Maleate USP/EP/BP, (dimethylamino)but-2-enamide maleate, (2E)-N-(4-{[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino}-3-c..., (E)-N-{4-[3-chloro-4-(pyridin-2-yl methoxy) anilino]-3-cyano-7-ethoxyquinolin-6-yl}-4-

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P264 + P265, P270, P273, P280, P301 + P317, P305 + P351 + P338, P318, P319, P330, P337 + P317, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Neratinib Maleate?

The CAS Registry Number of Neratinib Maleate is 915942-22-2. It is also known as Nerlynx, hki-272 maleate, Neratinib (maleate).

What is the molecular formula and molecular weight of Neratinib Maleate?

Neratinib Maleate has the molecular formula C34H33ClN6O7 and a molecular weight of 673.1 g/mol.

What is Neratinib Maleate used for?

Neratinib Maleate is supplied as a characterised reference material related to Neratinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Neratinib Maleate can I order?

We supply Neratinib Maleate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Neratinib Maleate?

Yes. Every lot of Neratinib Maleate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Neratinib Maleate be shipped internationally?

Yes. Neratinib Maleate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.