Binimetinib Intermediate 5

Name: Binimetinib Intermediate 5
Brand: Vaqora Chemicals
SKU: VQ-013215

About Binimetinib Intermediate 5

Listed under CAS 918321-18-3, Binimetinib Intermediate 5 is a process intermediate or related compound of Binimetinib available from Vaqora Chemicals. Formula C8H8FN3O4, molecular weight 229.17 g/mol. The IUPAC name is methyl 2,4-diamino-3-fluoro-5-nitrobenzoate. Common synonyms include methyl 2,4-diamino-3-fluoro-5- nitrobenzoate and Methyl2,4-diamino-3-fluoro-5-nitrobenzoate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Binimetinib, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Binimetinib Intermediate 5 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Binimetinib

View every impurity, metabolite and intermediate we list for Binimetinib.

Binimetinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Binimetinib Intermediate 5
Catalogue No.	VQ-013215
CAS Number	918321-18-3
IUPAC name	methyl 2,4-diamino-3-fluoro-5-nitrobenzoate
Molecular formula	C₈H₈FN₃O₄
Molecular weight	229.17 g/mol
Exact mass	229.0499
Grade	Reference Standard
HSN code	2933
InChIKey	RBALXPMHIYPOBI-UHFFFAOYSA-N
SMILES	COC(=O)C1=CC(=C(C(=C1N)F)N)[N+](=O)[O-]
PubChem CID	59365494

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	2 / 7
TPSA	124 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Binimetinib Intermediate 5?

The CAS Registry Number of Binimetinib Intermediate 5 is 918321-18-3. It is also known as methyl 2,4-diamino-3-fluoro-5- nitrobenzoate, Benzoic acid, 2,4-diamino-3-fluoro-5-nitro-, methyl ester, Methyl2,4-diamino-3-fluoro-5-nitrobenzoate.

What is the molecular formula and molecular weight of Binimetinib Intermediate 5?

Binimetinib Intermediate 5 has the molecular formula C8H8FN3O4 and a molecular weight of 229.17 g/mol. Its IUPAC name is methyl 2,4-diamino-3-fluoro-5-nitrobenzoate.

What is Binimetinib Intermediate 5 used for?

Binimetinib Intermediate 5 is supplied as a characterised reference material related to Binimetinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Binimetinib Intermediate 5 can I order?

We supply Binimetinib Intermediate 5 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Binimetinib Intermediate 5?

Yes. Every lot of Binimetinib Intermediate 5 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Binimetinib Intermediate 5 be shipped internationally?

Yes. Binimetinib Intermediate 5 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.