Trimethoprim EP Impurity D

Name: Trimethoprim EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-028540

About Trimethoprim EP Impurity D

Listed under CAS 92440-76-1, Trimethoprim EP Impurity D is a pharmacopeial impurity of Trimethoprim available from Vaqora Chemicals. With the molecular formula C14H17N3O4, it has a molar mass of 291.3 g/mol. The IUPAC name is 2-amino-5-[(3,4,5-trimethoxyphenyl)methyl]-1H-pyrimidin-6-one. Alternative names: Trimethoprim - Impurity D and 4-Desamino-4-hydroxy trimethoprim.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Trimethoprim impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Trimethoprim

View every impurity, metabolite and intermediate we list for Trimethoprim.

Trimethoprim impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Trimethoprim EP Impurity D
Catalogue No.	VQ-028540
CAS Number	92440-76-1
IUPAC name	2-amino-5-[(3,4,5-trimethoxyphenyl)methyl]-1H-pyrimidin-6-one
Molecular formula	C₁₄H₁₇N₃O₄
Molecular weight	291.3 g/mol
Exact mass	291.1219
Grade	Reference Standard
HSN code	38229090
InChIKey	ZKFZTBRMADDRMK-UHFFFAOYSA-N
SMILES	COC1=CC(=CC(=C1OC)OC)CC2=CN=C(NC2=O)N
PubChem CID	597783

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	2 / 5
TPSA	95.2 Å²
Synonyms	Trimethoprim - Impurity D, 2-Amino-5-((3,4,5-trimethoxyphenyl)methyl)-1H-pyrimidin-4-one, 2-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-4(1H)-pyrimidinone, 4-Desamino-4-hydroxy trimethoprim, 2-Amino-5-(3,4,5-trimethoxybenzyl)pyrimidin-4-ol, 2-Amino-5-(3,4,5-trimethoxybenzyl)-4-pyrimidinol #, 2-Amino-4-chloro-5-[3,4,5-trimethoxybenzyl]pyrimidine, 2-Amino-4-hydroxy-5-[3,4,5-trimethoxybenzyl]pyrimidine, 2-amino-5-(3,4,5-trimethoxybenzyl)pyrimidin-4(3H)-one, 2-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-4(3H)-pyrimidinone, 2-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidin-4(3H)-one, 2-azanyl-5-[(3,4,5-trimethoxyphenyl)methyl]-1H-pyrimidin-6-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trimethoprim EP Impurity D?

The CAS Registry Number of Trimethoprim EP Impurity D is 92440-76-1. It is also known as Trimethoprim - Impurity D, 2-Amino-5-((3,4,5-trimethoxyphenyl)methyl)-1H-pyrimidin-4-one, 2-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-4(1H)-pyrimidinone.

What is the molecular formula and molecular weight of Trimethoprim EP Impurity D?

Trimethoprim EP Impurity D has the molecular formula C14H17N3O4 and a molecular weight of 291.3 g/mol. Its IUPAC name is 2-amino-5-[(3,4,5-trimethoxyphenyl)methyl]-1H-pyrimidin-6-one.

What is Trimethoprim EP Impurity D used for?

Trimethoprim EP Impurity D is supplied as a characterised reference material related to Trimethoprim. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trimethoprim EP Impurity D can I order?

We supply Trimethoprim EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trimethoprim EP Impurity D?

Yes. Every lot of Trimethoprim EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trimethoprim EP Impurity D be shipped internationally?

Yes. Trimethoprim EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.