rac-Ruxolitinib

Name: rac-Ruxolitinib
Brand: Vaqora Chemicals
SKU: VQ-013753

About rac-Ruxolitinib

rac-Ruxolitinib (CAS 941688-05-7) is a process intermediate or related compound of Ruxolitinib offered by Vaqora Chemicals. The compound has the formula C17H18N6, corresponding to a molecular weight of 306.4 g/mol. The IUPAC name is 3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile. Alternative names: INCB018424 Racemic and (R)-ruxolitinib.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is a process intermediate or related compound in the synthesis of Ruxolitinib, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Ruxolitinib

View every impurity, metabolite and intermediate we list for Ruxolitinib.

Ruxolitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	rac-Ruxolitinib
Catalogue No.	VQ-013753
CAS Number	941688-05-7
IUPAC name	3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile
Molecular formula	C₁₇H₁₈N₆
Molecular weight	306.4 g/mol
Exact mass	306.1593
Grade	Reference Standard
HSN code	2933
InChIKey	HFNKQEVNSGCOJV-UHFFFAOYSA-N
SMILES	C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
PubChem CID	17754772

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	1 / 4
TPSA	83.2 Å²
Synonyms	3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile, β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile, INCB018424 Racemic, 3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1-pyrazolyl]propanenitrile, (R)-ruxolitinib, Ruxotinib Racemate, 3-[4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-cyclopentylpropanenitrile, ss-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile, Ruxolitinib racemic, (Rac)-Ruxolitinib, Kinome_3200, Kinome_3203

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of rac-Ruxolitinib?

The CAS Registry Number of rac-Ruxolitinib is 941688-05-7. It is also known as 3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile, β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile, INCB018424 Racemic.

What is the molecular formula and molecular weight of rac-Ruxolitinib?

rac-Ruxolitinib has the molecular formula C17H18N6 and a molecular weight of 306.4 g/mol. Its IUPAC name is 3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile.

What is rac-Ruxolitinib used for?

rac-Ruxolitinib is supplied as a characterised reference material related to Ruxolitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of rac-Ruxolitinib can I order?

We supply rac-Ruxolitinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with rac-Ruxolitinib?

Yes. Every lot of rac-Ruxolitinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can rac-Ruxolitinib be shipped internationally?

Yes. We export rac-Ruxolitinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.