Sildenafil-d8

Name: Sildenafil-d8
Brand: Vaqora Chemicals
SKU: VQ-033843

About Sildenafil-d8

Vaqora Chemicals supplies Sildenafil-d8, a stable isotope labelled analogue related to Sildenafil registered under CAS number 951385-68-5. Formula C22H30N6O4S, molecular weight 482.6 g/mol. It is also known as Sildenafil-d8 (piperazine-d8) or TMID-0043.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Sildenafil and related analytes in bioanalytical, pharmacokinetic and impurity studies. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sildenafil-d8 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Sildenafil

View every impurity, metabolite and intermediate we list for Sildenafil.

Sildenafil impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Sildenafil-d8
Catalogue No.	VQ-033843
CAS Number	951385-68-5
IUPAC name	5-[2-ethoxy-5-(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-7-one
Molecular formula	C₂₂H₃₀N₆O₄S
Molecular weight	482.6 g/mol
Exact mass	482.2551
Grade	Reference Standard
HSN code	38229090
InChIKey	BNRNXUUZRGQAQC-BGKXKQMNSA-N
SMILES	[2H]C1(C(N(C(C(N1C)([2H])[2H])([2H])[2H])S(=O)(=O)C2=CC(=C(C=C2)OCC)C3=NC4=C(C(=O)N3)N(N=C4CCC)C)([2H])[2H])[2H]
PubChem CID	135949536

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	1 / 8
TPSA	118 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sildenafil-d8?

The CAS Registry Number of Sildenafil-d8 is 951385-68-5. It is also known as Sildenafil-d8 (piperazine-d8), TMID-0043.

What is the molecular formula and molecular weight of Sildenafil-d8?

Sildenafil-d8 has the molecular formula C22H30N6O4S and a molecular weight of 482.6 g/mol. Its IUPAC name is 5-[2-ethoxy-5-(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-7-one.

What is Sildenafil-d8 used for?

Sildenafil-d8 is supplied as a characterised reference material related to Sildenafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sildenafil-d8 can I order?

We supply Sildenafil-d8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sildenafil-d8?

Yes. Every lot of Sildenafil-d8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sildenafil-d8 be shipped internationally?

Yes. We export Sildenafil-d8 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.