Tadalafil-d3

About Tadalafil-d3

Tadalafil-d3 is a stable isotope labelled analogue related to Tadalafil carrying the CAS registry number 960226-55-5. The compound has the formula C22H19N3O4, corresponding to a molecular weight of 392.4 g/mol. Common synonyms include (6R,12aR)-Tadalafil-d3 (N-methyl-d3) and Tadalafi-d3.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Tadalafil and related analytes in bioanalytical, pharmacokinetic and impurity studies. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Tadalafil-d3 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Tadalafil

View every impurity, metabolite and intermediate we list for Tadalafil.

Tadalafil impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Tadalafil-d3
Catalogue No.	VQ-034024
CAS Number	960226-55-5
IUPAC name	(2R,8R)-2-(1,3-benzodioxol-5-yl)-6-(trideuteriomethyl)-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione
Molecular formula	C₂₂H₁₉N₃O₄
Molecular weight	392.4 g/mol
Exact mass	392.1564
Grade	Reference Standard
HSN code	38229090
InChIKey	WOXKDUGGOYFFRN-WFMNTJQSSA-N
SMILES	[2H]C([2H])([2H])N1CC(=O)N2[C@@H](C1=O)CC3=C([C@H]2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36
PubChem CID	46782966

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 4
TPSA	74.9 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tadalafil-d3?

The CAS Registry Number of Tadalafil-d3 is 960226-55-5. It is also known as (6R,12aR)-Tadalafil-d3 (N-methyl-d3), Tadalafi-d3, TMID-0037.

What is the molecular formula and molecular weight of Tadalafil-d3?

Tadalafil-d3 has the molecular formula C22H19N3O4 and a molecular weight of 392.4 g/mol. Its IUPAC name is (2R,8R)-2-(1,3-benzodioxol-5-yl)-6-(trideuteriomethyl)-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione.

What is Tadalafil-d3 used for?

Tadalafil-d3 is supplied as a characterised reference material related to Tadalafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tadalafil-d3 can I order?

We supply Tadalafil-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tadalafil-d3?

Yes. Every lot of Tadalafil-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tadalafil-d3 be shipped internationally?

Yes. We export Tadalafil-d3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.