2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminopheny… 2410284-89-6

Name: 2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide)
Brand: Vaqora Chemicals
SKU: VQ-026917

About 2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide)

Listed under CAS 2410284-89-6, 2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide) is an impurity of Nintedanib available from Vaqora Chemicals. Its molecular formula is C22H30N6O2 and its molecular weight is 410.5 g/mol. The IUPAC name is 2-[4-[2-(4-amino-N-methylanilino)-2-oxoethyl]piperazin-1-yl]-N-(4-aminophenyl)-N-methylacetamide. Alternative names: Nintedanib Dimer.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Nintedanib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide)
Catalogue No.	VQ-026917
CAS Number	2410284-89-6
IUPAC name	2-[4-[2-(4-amino-N-methylanilino)-2-oxoethyl]piperazin-1-yl]-N-(4-aminophenyl)-N-methylacetamide
Molecular formula	C₂₂H₃₀N₆O₂
Molecular weight	410.5 g/mol
Exact mass	410.243
Grade	Reference Standard
HSN code	38229090
InChIKey	RBOFHNBKFHHSEJ-UHFFFAOYSA-N
SMILES	CN(C1=CC=C(C=C1)N)C(=O)CN2CCN(CC2)CC(=O)N(C)C3=CC=C(C=C3)N
PubChem CID	145714460

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	2 / 6
TPSA	99.1 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide)?

The CAS Registry Number of 2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide) is 2410284-89-6. It is also known as Nintedanib Dimer, N1,N4-Bis(4-aminophenyl)-N1,N4-dimethyl-1,4-piperazinediacetamide, 1,4-Piperazinediacetamide, N1,N4-bis(4-aminophenyl)-N1,N4-dimethyl-.

What is the molecular formula and molecular weight of 2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide)?

2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide) has the molecular formula C22H30N6O2 and a molecular weight of 410.5 g/mol. Its IUPAC name is 2-[4-[2-(4-amino-N-methylanilino)-2-oxoethyl]piperazin-1-yl]-N-(4-aminophenyl)-N-methylacetamide.

What is 2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide) used for?

2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide) is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide) can I order?

We supply 2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide)?

Yes. Every lot of 2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide) be shipped internationally?

Yes. 2,2'-(Piperazine-1,4-diyl)bis(N-(4-aminophenyl)-N-methylacetamide) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.