6-Carboxyoxindole

Name: 6-Carboxyoxindole
Brand: Vaqora Chemicals
SKU: VQ-026915

About 6-Carboxyoxindole

Vaqora Chemicals supplies 6-Carboxyoxindole, an impurity of Nintedanib registered under CAS number 334952-09-9. Formula C9H7NO3, molecular weight 177.16 g/mol. Its systematic (IUPAC) name is 2-oxo-1,3-dihydroindole-6-carboxylic acid. Common synonyms include 2-oxoindoline-6-carboxylic acid and 2-Oxo-2,3-dihydro-1H-indole-6-carboxylic acid.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Nintedanib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 6-Carboxyoxindole in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Carboxyoxindole
Catalogue No.	VQ-026915
CAS Number	334952-09-9
IUPAC name	2-oxo-1,3-dihydroindole-6-carboxylic acid
Molecular formula	C₉H₇NO₃
Molecular weight	177.16 g/mol
Exact mass	177.0426
Grade	Reference Standard
HSN code	38229090
InChIKey	IIKVTJWRBSYRSA-UHFFFAOYSA-N
SMILES	C1C2=C(C=C(C=C2)C(=O)O)NC1=O
PubChem CID	7213323

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	2 / 3
TPSA	66.4 Å²
Synonyms	2-oxoindoline-6-carboxylic acid, 2-Oxo-2,3-dihydro-1H-indole-6-carboxylic acid, 2-Oxo-indoline-6-carboxylic Acid, 1H-Indole-6-carboxylic acid, 2,3-dihydro-2-oxo-, 2-oxoindoline-6-carboxylicacid, 2-indolinone-6-carboxylic acid, 2-oxo-6-indolinecarboxylic acid, 1H-Indole-6-carboxylic acid, 2

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Carboxyoxindole?

The CAS Registry Number of 6-Carboxyoxindole is 334952-09-9. It is also known as 2-oxoindoline-6-carboxylic acid, 2-Oxo-2,3-dihydro-1H-indole-6-carboxylic acid, 2-Oxo-indoline-6-carboxylic Acid.

What is the molecular formula and molecular weight of 6-Carboxyoxindole?

6-Carboxyoxindole has the molecular formula C9H7NO3 and a molecular weight of 177.16 g/mol. Its IUPAC name is 2-oxo-1,3-dihydroindole-6-carboxylic acid.

What is 6-Carboxyoxindole used for?

6-Carboxyoxindole is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Carboxyoxindole can I order?

We supply 6-Carboxyoxindole in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Carboxyoxindole?

Yes. Every lot of 6-Carboxyoxindole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Carboxyoxindole be shipped internationally?

Yes. 6-Carboxyoxindole is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.