3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-met… 1300690-48-5

Name: 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid
Brand: Vaqora Chemicals
SKU: VQ-023517

About 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid

Vaqora Chemicals supplies 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid, a metabolite or degradation product of Ponatinib registered under CAS number 1300690-48-5. Its molecular formula is C16H11N3O2 and its molecular weight is 277.28 g/mol. Its systematic (IUPAC) name is 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic acid. It is also known as Ponatinib Rc 7.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Ponatinib, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ponatinib

View every impurity, metabolite and intermediate we list for Ponatinib.

Ponatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid
Catalogue No.	VQ-023517
CAS Number	1300690-48-5
IUPAC name	3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic acid
Molecular formula	C₁₆H₁₁N₃O₂
Molecular weight	277.28 g/mol
Exact mass	277.0851
Grade	Reference Standard
HSN code	38229090
InChIKey	SCMPXDBRMCTALZ-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)C(=O)O)C#CC2=CN=C3N2N=CC=C3
PubChem CID	58945624

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 4
TPSA	67.5 Å²
Synonyms	Benzoic acid, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-, Benzoic acid, 3-(2-imidazo(1,2-b)pyridazin-3-ylethynyl)-4-methyl-, 3-(2-{imidazo[1,2-b]pyridazin-3-yl}ethynyl)-4-methylbenzoic acid, 3-(2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl)-4-methylbenzoic acid, Ponatinib Rc 7, 3-(3-Imidazo[1,2-b]pyridazinylethynyl)-4-methylbenzoic Acid, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-benzoic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid?

The CAS Registry Number of 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid is 1300690-48-5. It is also known as Benzoic acid, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-, Benzoic acid, 3-(2-imidazo(1,2-b)pyridazin-3-ylethynyl)-4-methyl-, 3-(2-{imidazo[1,2-b]pyridazin-3-yl}ethynyl)-4-methylbenzoic acid.

What is the molecular formula and molecular weight of 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid?

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid has the molecular formula C16H11N3O2 and a molecular weight of 277.28 g/mol. Its IUPAC name is 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic acid.

What is 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid used for?

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid is supplied as a characterised reference material related to Ponatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid can I order?

We supply 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid?

Yes. Every lot of 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid be shipped internationally?

Yes. We export 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.