![3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine chemical structure](/media/structures/AUMLXDLZHWMUCA-UHFFFAOYSA-N.svg)
3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine
- CAS
- 943320-60-3
- Formula
- C11H13N3Si
- MW
- 215.33 g/mol
VQ-041555
Impurity reference standards
Ponatinib impurities & reference standards
Characterised Ponatinib impurities, degradation products and related compounds for analytical method development, validation, QC release and regulatory filings.
12reference materials
1nitrosamine impurities
COAHPLC · NMR · MS on request
![3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid chemical structure](/media/structures/SCMPXDBRMCTALZ-UHFFFAOYSA-N.svg)
3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid
- CAS
- 1300690-48-5
- Formula
- C16H11N3O2
- MW
- 277.28 g/mol
VQ-023517
![3-Ethynylimidazo[1,2-b]pyridazine chemical structure](/media/structures/VYOHSFQVMLAURO-UHFFFAOYSA-N.svg)
3,3-(Buta-1,3-diyne-1,4-diyl)bis(4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide)
- CAS
- 2097674-16-1
- Formula
- C46H46F6N6O2
- MW
- 828.9 g/mol
VQ-023516
4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
- CAS
- 694499-26-8
- Formula
- C13H18F3N3
- MW
- 273.3 g/mol
VQ-023514
FAQs — Ponatinib impurities
Which Ponatinib impurities do you supply?
We list 12 Ponatinib-related reference materials, including process impurities, degradation products, nitrosamine impurities and related compounds. Each is supplied with a COA, and characterisation data (HPLC, 1H-NMR, MS, IR) can be provided on request.
What are Ponatinib impurity standards used for?
They are used for analytical method development and validation, impurity identification and quantification, forced-degradation and stability studies, and to support ANDA, DMF and other regulatory submissions under ICH Q3A/Q3B (and ICH M7 for mutagenic impurities).
Can you synthesise a Ponatinib impurity that is not listed?
Yes. Our custom synthesis service can prepare and characterise unlisted impurities, metabolites and labelled analogues from milligram to gram scale. Share the structure or name and required quantity for a quotation.
Request Ponatinib impurity standards
We reply within one business day with price, pack options, lead time and documentation.