Ponatinib N-Oxide

Name: Ponatinib N-Oxide
Brand: Vaqora Chemicals
SKU: VQ-021312

About Ponatinib N-Oxide

Ponatinib N-Oxide is a metabolite or degradation product of Ponatinib carrying the CAS registry number 2227480-51-3. With the molecular formula C29H27F3N6O2, it has a molar mass of 548.6 g/mol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Ponatinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ponatinib

View every impurity, metabolite and intermediate we list for Ponatinib.

Ponatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ponatinib N-Oxide
Catalogue No.	VQ-021312
CAS Number	2227480-51-3
IUPAC name	3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-4-oxidopiperazin-4-ium-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
Molecular formula	C₂₉H₂₇F₃N₆O₂
Molecular weight	548.6 g/mol
Exact mass	548.2148
Grade	Reference Standard
HSN code	38229090
InChIKey	QLWXUMFIMUKGLE-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CC[N+](CC3)(C)[O-])C(F)(F)F)C#CC4=CN=C5N4N=CC=C5
PubChem CID	129851389

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	1 / 8
TPSA	80.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ponatinib N-Oxide?

The CAS Registry Number of Ponatinib N-Oxide is 2227480-51-3.

What is the molecular formula and molecular weight of Ponatinib N-Oxide?

Ponatinib N-Oxide has the molecular formula C29H27F3N6O2 and a molecular weight of 548.6 g/mol. Its IUPAC name is 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-4-oxidopiperazin-4-ium-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide.

What is Ponatinib N-Oxide used for?

Ponatinib N-Oxide is supplied as a characterised reference material related to Ponatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ponatinib N-Oxide can I order?

We supply Ponatinib N-Oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ponatinib N-Oxide?

Yes. Every lot of Ponatinib N-Oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ponatinib N-Oxide be shipped internationally?

Yes. We export Ponatinib N-Oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.