Ponatinib D8

Name: Ponatinib D8
Brand: Vaqora Chemicals
SKU: VQ-033245

About Ponatinib D8

Ponatinib D8 (CAS 1562993-37-6) is a stable isotope labelled analogue related to Ponatinib offered by Vaqora Chemicals. With the molecular formula C29H27F3N6O, it has a molar mass of 540.6 g/mol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Ponatinib D8 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Ponatinib

View every impurity, metabolite and intermediate we list for Ponatinib.

Ponatinib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ponatinib D8
Catalogue No.	VQ-033245
CAS Number	1562993-37-6
IUPAC name	3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
Molecular formula	C₂₉H₂₇F₃N₆O
Molecular weight	540.6 g/mol
Exact mass	540.2701
Grade	Reference Standard
HSN code	38229090
InChIKey	PHXJVRSECIGDHY-DHNBGMNGSA-N
SMILES	[2H]C1(C(N(C(C(N1C)([2H])[2H])([2H])[2H])CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)C#CC4=CN=C5N4N=CC=C5)C(F)(F)F)([2H])[2H])[2H]
PubChem CID	73214034

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	1 / 8
TPSA	65.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ponatinib D8?

The CAS Registry Number of Ponatinib D8 is 1562993-37-6.

What is the molecular formula and molecular weight of Ponatinib D8?

Ponatinib D8 has the molecular formula C29H27F3N6O and a molecular weight of 540.6 g/mol. Its IUPAC name is 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide.

What is Ponatinib D8 used for?

Ponatinib D8 is supplied as a characterised reference material related to Ponatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ponatinib D8 can I order?

We supply Ponatinib D8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ponatinib D8?

Yes. Every lot of Ponatinib D8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ponatinib D8 be shipped internationally?

Yes. We export Ponatinib D8 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.