(3S,4S)-Tofacitinib

Name: (3S,4S)-Tofacitinib
Brand: Vaqora Chemicals
SKU: VQ-023910

About (3S,4S)-Tofacitinib

(3S,4S)-Tofacitinib (CAS 1092578-47-6) is a high-purity reference standard of Tofacitinib offered by Vaqora Chemicals. With the molecular formula C16H20N6O, it has a molar mass of 312.37 g/mol. Systematically, it is named 3-[(3S,4S)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile. Alternative names: Tofacitinib enantiomer and (-)-Tofacitinib.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a reference sample of Tofacitinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (3S,4S)-Tofacitinib is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Tofacitinib

View every impurity, metabolite and intermediate we list for Tofacitinib.

Tofacitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	(3S,4S)-Tofacitinib
Catalogue No.	VQ-023910
CAS Number	1092578-47-6
IUPAC name	3-[(3S,4S)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile
Molecular formula	C₁₆H₂₀N₆O
Molecular weight	312.37 g/mol
Exact mass	312.1699
Grade	Reference Standard
HSN code	38229090
InChIKey	UJLAWZDWDVHWOW-WCQYABFASA-N
SMILES	C[C@H]1CCN(C[C@H]1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N
PubChem CID	20111936

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	1 / 5
TPSA	88.9 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (3S,4S)-Tofacitinib?

The CAS Registry Number of (3S,4S)-Tofacitinib is 1092578-47-6. It is also known as Tofacitinib enantiomer, (-)-Tofacitinib, Tofacitinib, (3S,4S)-.

What is the molecular formula and molecular weight of (3S,4S)-Tofacitinib?

(3S,4S)-Tofacitinib has the molecular formula C16H20N6O and a molecular weight of 312.37 g/mol. Its IUPAC name is 3-[(3S,4S)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile.

What is (3S,4S)-Tofacitinib used for?

(3S,4S)-Tofacitinib is supplied as a characterised reference material related to Tofacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (3S,4S)-Tofacitinib can I order?

We supply (3S,4S)-Tofacitinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (3S,4S)-Tofacitinib?

Yes. Every lot of (3S,4S)-Tofacitinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (3S,4S)-Tofacitinib be shipped internationally?

Yes. We export (3S,4S)-Tofacitinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.