4-Amino-3-methyl benzoic acid

Name: 4-Amino-3-methyl benzoic acid
Brand: Vaqora Chemicals
SKU: VQ-040257

About 4-Amino-3-methyl benzoic acid

4-Amino-3-methyl benzoic acid (CAS 2486-70-6) is an impurity of Nilotinib offered by Vaqora Chemicals. Formula C8H9NO2, molecular weight 151.16 g/mol. It is also known as 3-methyl-4-aminobenzoic acid or Benzoic acid, 4-amino-3-methyl-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Nilotinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Amino-3-methyl benzoic acid
Catalogue No.	VQ-040257
CAS Number	2486-70-6
IUPAC name	4-amino-3-methylbenzoic acid
Molecular formula	C₈H₉NO₂
Molecular weight	151.16 g/mol
Exact mass	151.0633
Grade	Reference Standard
HSN code	38229090
InChIKey	NHFKECPTBZZFBC-UHFFFAOYSA-N
SMILES	CC1=C(C=CC(=C1)C(=O)O)N
PubChem CID	75598

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	2 / 3
TPSA	63.3 Å²
Synonyms	3-methyl-4-aminobenzoic acid, Benzoic acid, 4-amino-3-methyl-, 4-Amino-m-toluic acid, Benzoic acid, 3-methyl-4-amino, 4-amino-3-methylbenzenecarboxylic acid, 4-amino-3-methyl benzoate, 4-amino-3-methylbenzoic

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Amino-3-methyl benzoic acid?

The CAS Registry Number of 4-Amino-3-methyl benzoic acid is 2486-70-6. It is also known as 3-methyl-4-aminobenzoic acid, Benzoic acid, 4-amino-3-methyl-, 4-Amino-m-toluic acid.

What is the molecular formula and molecular weight of 4-Amino-3-methyl benzoic acid?

4-Amino-3-methyl benzoic acid has the molecular formula C8H9NO2 and a molecular weight of 151.16 g/mol. Its IUPAC name is 4-amino-3-methylbenzoic acid.

What is 4-Amino-3-methyl benzoic acid used for?

4-Amino-3-methyl benzoic acid is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Amino-3-methyl benzoic acid can I order?

We supply 4-Amino-3-methyl benzoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Amino-3-methyl benzoic acid?

Yes. Every lot of 4-Amino-3-methyl benzoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Amino-3-methyl benzoic acid be shipped internationally?

Yes. 4-Amino-3-methyl benzoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.