Nilotinib-d6

Name: Nilotinib-d6
Brand: Vaqora Chemicals
SKU: VQ-038646

About Nilotinib-d6

Vaqora Chemicals supplies Nilotinib-d6, a stable isotope labelled analogue related to Nilotinib registered under CAS number 1268356-17-7. The compound has the formula C28H22F3N7O, corresponding to a molecular weight of 535.6 g/mol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Nilotinib-d6 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Nilotinib-d6
Catalogue No.	VQ-038646
CAS Number	1268356-17-7
IUPAC name	2,3,6-trideuterio-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-5-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-4-(trideuteriomethyl)benzamide
Molecular formula	C₂₈H₂₂F₃N₇O
Molecular weight	535.6 g/mol
Exact mass	535.2215
Grade	Reference Standard
HSN code	38229090
InChIKey	HHZIURLSWUIHRB-AGINCAKFSA-N
SMILES	[2H]C1=C(C(=C(C(=C1C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)[2H])NC4=NC=CC(=N4)C5=CN=CC=C5)C([2H])([2H])[2H])[2H]
PubChem CID	131667930

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	2 / 9
TPSA	97.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nilotinib-d6?

The CAS Registry Number of Nilotinib-d6 is 1268356-17-7.

What is the molecular formula and molecular weight of Nilotinib-d6?

Nilotinib-d6 has the molecular formula C28H22F3N7O and a molecular weight of 535.6 g/mol. Its IUPAC name is 2,3,6-trideuterio-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-5-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-4-(trideuteriomethyl)benzamide.

What is Nilotinib-d6 used for?

Nilotinib-d6 is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nilotinib-d6 can I order?

We supply Nilotinib-d6 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nilotinib-d6?

Yes. Every lot of Nilotinib-d6 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nilotinib-d6 be shipped internationally?

Yes. We export Nilotinib-d6 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.