Nilotinib hydrochloride dihydrate

Name: Nilotinib hydrochloride dihydrate
Brand: Vaqora Chemicals
SKU: VQ-038641

About Nilotinib hydrochloride dihydrate

Nilotinib hydrochloride dihydrate is a high-purity reference standard of Nilotinib carrying the CAS registry number 923289-71-8. The compound has the formula C28H27ClF3N7O3, corresponding to a molecular weight of 602.0 g/mol. Alternative names: Nilotinib monohydrochloride dihydrate and Nilotinib hydrochloride dihydrate (JAN).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a reference sample of Nilotinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Nilotinib hydrochloride dihydrate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nilotinib hydrochloride dihydrate
Catalogue No.	VQ-038641
CAS Number	923289-71-8
IUPAC name	4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide;dihydrate;hydrochloride
Molecular formula	C₂₈H₂₇ClF₃N₇O₃
Molecular weight	602 g/mol
Exact mass	601.1816
Grade	Reference Standard
HSN code	38229090
InChIKey	SDOLNFCUZATHSO-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.O.O.Cl
PubChem CID	67323320

Physical properties
Physical form	Solid
H-bond donors / acceptors	5 / 11
TPSA	99.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nilotinib hydrochloride dihydrate?

The CAS Registry Number of Nilotinib hydrochloride dihydrate is 923289-71-8. It is also known as Nilotinib monohydrochloride dihydrate, Nilotinib hydrochloride dihydrate (JAN).

What is the molecular formula and molecular weight of Nilotinib hydrochloride dihydrate?

Nilotinib hydrochloride dihydrate has the molecular formula C28H27ClF3N7O3 and a molecular weight of 602 g/mol.

What is Nilotinib hydrochloride dihydrate used for?

Nilotinib hydrochloride dihydrate is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nilotinib hydrochloride dihydrate can I order?

We supply Nilotinib hydrochloride dihydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nilotinib hydrochloride dihydrate?

Yes. Every lot of Nilotinib hydrochloride dihydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nilotinib hydrochloride dihydrate be shipped internationally?

Yes. We export Nilotinib hydrochloride dihydrate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.