3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromet… 641571-18-8

Name: 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid
Brand: Vaqora Chemicals
SKU: VQ-038643

About 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid

Listed under CAS 641571-18-8, 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid is an impurity of Nilotinib available from Vaqora Chemicals. Formula C12H9F3N2O2, molecular weight 270.21 g/mol. Its systematic (IUPAC) name is 3-(5-methylimidazol-1-yl)-5-(trifluoromethyl)benzoic acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Nilotinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid
Catalogue No.	VQ-038643
CAS Number	641571-18-8
IUPAC name	3-(5-methylimidazol-1-yl)-5-(trifluoromethyl)benzoic acid
Molecular formula	C₁₂H₉F₃N₂O₂
Molecular weight	270.21 g/mol
Exact mass	270.0616
Grade	Reference Standard
HSN code	38229090
InChIKey	GGSUKVFTTLTIJG-UHFFFAOYSA-N
SMILES	CC1=CN=CN1C2=CC(=CC(=C2)C(F)(F)F)C(=O)O
PubChem CID	67213701

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 6
TPSA	55.1 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid?

The CAS Registry Number of 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid is 641571-18-8.

What is the molecular formula and molecular weight of 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid?

3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid has the molecular formula C12H9F3N2O2 and a molecular weight of 270.21 g/mol. Its IUPAC name is 3-(5-methylimidazol-1-yl)-5-(trifluoromethyl)benzoic acid.

What is 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid used for?

3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid can I order?

We supply 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid?

Yes. Every lot of 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid be shipped internationally?

Yes. 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.