(4-(Methylamino)benzoyl)-D-glutamic acid

Name: (4-(Methylamino)benzoyl)-D-glutamic acid
Brand: Vaqora Chemicals
SKU: VQ-026636

About (4-(Methylamino)benzoyl)-D-glutamic acid

(4-(Methylamino)benzoyl)-D-glutamic acid (CAS 52030-86-1) is an impurity of Methotrexate offered by Vaqora Chemicals. With the molecular formula C13H16N2O5, it has a molar mass of 280.28 g/mol. Systematically, it is named (2R)-2-[[4-(methylamino)benzoyl]amino]pentanedioic acid. Common synonyms include D-Glutamic acid, N-[4-(methylamino)benzoyl]- and N-[4-(Methylamino)benzoyl]-D-glutamic acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Methotrexate, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (4-(Methylamino)benzoyl)-D-glutamic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	(4-(Methylamino)benzoyl)-D-glutamic acid
Catalogue No.	VQ-026636
CAS Number	52030-86-1
IUPAC name	(2R)-2-[[4-(methylamino)benzoyl]amino]pentanedioic acid
Molecular formula	C₁₃H₁₆N₂O₅
Molecular weight	280.28 g/mol
Exact mass	280.1059
Grade	Reference Standard
HSN code	38229090
InChIKey	UFBUCKLNZUNJHS-SNVBAGLBSA-N
SMILES	CNC1=CC=C(C=C1)C(=O)N[C@H](CCC(=O)O)C(=O)O
PubChem CID	54350039

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	4 / 6
TPSA	116 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (4-(Methylamino)benzoyl)-D-glutamic acid?

The CAS Registry Number of (4-(Methylamino)benzoyl)-D-glutamic acid is 52030-86-1. It is also known as D-Glutamic acid, N-[4-(methylamino)benzoyl]-, N-[4-(Methylamino)benzoyl]-D-glutamic acid, 2-[[4-(methylamino)benzoyl]amino]pentanedioic acid, (2R)-.

What is the molecular formula and molecular weight of (4-(Methylamino)benzoyl)-D-glutamic acid?

(4-(Methylamino)benzoyl)-D-glutamic acid has the molecular formula C13H16N2O5 and a molecular weight of 280.28 g/mol. Its IUPAC name is (2R)-2-[[4-(methylamino)benzoyl]amino]pentanedioic acid.

What is (4-(Methylamino)benzoyl)-D-glutamic acid used for?

(4-(Methylamino)benzoyl)-D-glutamic acid is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (4-(Methylamino)benzoyl)-D-glutamic acid can I order?

We supply (4-(Methylamino)benzoyl)-D-glutamic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (4-(Methylamino)benzoyl)-D-glutamic acid?

Yes. Every lot of (4-(Methylamino)benzoyl)-D-glutamic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (4-(Methylamino)benzoyl)-D-glutamic acid be shipped internationally?

Yes. We export (4-(Methylamino)benzoyl)-D-glutamic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.